J
Judy K. Shigenaga
Researcher at University of California, San Francisco
Publications - 70
Citations - 7418
Judy K. Shigenaga is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Tumor necrosis factor alpha & Receptor. The author has an hindex of 43, co-authored 69 publications receiving 6908 citations. Previous affiliations of Judy K. Shigenaga include United States Department of Veterans Affairs & San Francisco General Hospital.
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Journal ArticleDOI
Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host.
Weerapan Khovidhunkit,Min Sun Kim,Riaz A. Memon,Judy K. Shigenaga,Arthur H. Moser,Kenneth R. Feingold,Carl Grunfeld +6 more
TL;DR: APR-induced alterations initially protect the host from the harmful effects of bacteria, viruses, and parasites, however, if prolonged, these changes in the structure and function of lipoproteins will contribute to atherogenesis.
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Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome.
Carl Grunfeld,Miyin Pang,William T. Doerrler,Judy K. Shigenaga,Peter S. Jensen,Kenneth R. Feingold +5 more
TL;DR: In this article, the authors studied plasma lipids, lipoproteins, triglyceride (TG) metabolism, and serum cytokines in three groups: patients with the acquired immunodeficiency syndrome (AIDS) without active secondary infection, patients with evidence of HIV infection but without clinical AIDS (HIV+), and controls.
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Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance.
Kenneth R. Feingold,Ilona Staprans,Riaz A. Memon,A H Moser,Judy K. Shigenaga,William T. Doerrler,C A Dinarello,Carl Grunfeld +7 more
TL;DR: The data suggest that neither of these cytokines is absolutely required for the increase in serum triglycerides induced by LPS, raising the possibility that other cytokines, small molecular mediators, or LPS itself may play a crucial role.
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Resting energy expenditure, caloric intake, and short-term weight change in human immunodeficiency virus infection and the acquired immunodeficiency syndrome.
Carl Grunfeld,Miyin Pang,Laurie Shimizu,Judy K. Shigenaga,Peter S. Jensen,Kenneth R. Feingold +5 more
TL;DR: HIV+ and AIDS are able to partially compensate for increased REE because they do not show short-term weight loss, and rapid weight loss with anorexia may be a harbinger of secondary infection in AIDS.
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The acute phase response is associated with retinoid X receptor repression in rodent liver.
TL;DR: It is demonstrated that lipopolysaccharide (LPS) induces a rapid, dose-dependent decrease in RXRα, RXRβ, and RXRγ proteins in hamster liver, and increased RNA degradation is likely responsible for the repression of RXR.