J
Judy Stone
Researcher at Memorial Hospital of South Bend
Publications - 4
Citations - 1010
Judy Stone is an academic researcher from Memorial Hospital of South Bend. The author has contributed to research in topics: Chemotherapy & Tissue factor pathway inhibitor. The author has an hindex of 4, co-authored 4 publications receiving 979 citations.
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Journal ArticleDOI
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial.
Edward Abraham,Konrad Reinhart,Steven M. Opal,Ignace Demeyer,Christopher J. Doig,Angel López Rodriguez,Richard Beale,Petr Svoboda,Pierre-François Laterre,Stuart Simon,Bruce Light,Herbert Spapen,Judy Stone,Allan Seibert,Claus Peckelsen,Cathy De Deyne,Russell Postier,Ville Pettilä,Charles L. Sprung,Antonio Artigas,Sandra Percell,Vincent Shu,Christian Zwingelstein,Jeffrey Tobias,Lona Poole,James C. Stolzenbach,Abla A. Creasey +26 more
TL;DR: Treatment with tifacogin had no effect on all-cause mortality in patients with severe sepsis and high INR and tifACogin administration was associated with an increase in risk of bleeding, irrespective of baseline INR.
Journal ArticleDOI
A Randomized Controlled Trial of Filgrastim for the Treatment of Hospitalized Patients with Multilobar Pneumonia
Steve Nelson,Albrecht M. Heyder,Judy Stone,Michel G. Bergeron,Steven Daugherty,Gregory Peterson,Nick Fotheringham,William Welch,Steven Milwee,Richard K. Root +9 more
TL;DR: There was a trend toward reduction of mortality in patients with pneumococcal bacteremia and filgrastim was safe and well tolerated when administered to patients with multilobar CAP.
Journal ArticleDOI
Pseudoepidemic of urinary tract infections due to Trichosporon beigelii.
Judy Stone,Robert Manasse +1 more
TL;DR: In-services to nursing and housekeeping personnel in the proper collection of urine specimens and cleaning of potentially contaminated items, the replacement of metal urine graduates with disposable plastic ones and increased monitoring of personnel's activities stopped the outbreak abruptly.
Efficacy and Safety of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) in Severe Sepsis
Edward Abraham,Steven M. Opal,Ignace Demeyer,Richard Beale,Petr Svoboda,Stuart Simon,Bruce Light,Judy Stone,Claus Peckelsen,Cathy De Deyne,Ville Pettilä,Charles L. Sprung,Sandra Percell,Vincent Shu,Lona Poole,James C. Stolzenbach,Abla A. Creasey +16 more
TL;DR: The expression and release of tissue factor is a major trigger for the activation of coagulation in patients with sepsis and TFPI forms a complex with tissue factor and blood protease factors leading to inhibition of thrombin generation and fibrin formation.