Julia S. Kimbell

TL;DR: A three-dimensional, anatomically accurate representation of an adult human nasal cavity and nasopharynx was constructed and airflow was streamlined in the main nasal passages and complex in the vestibul...

TL;DR: In this article, the inertial particle deposition efficiency of two replicas of the same nasal airways manufactured by different stereolithography machines was determined and compared results with deposition efficiencies reported for other techniques from the same magnetic resonance imaging scans.

TL;DR: Simulations of water transport in the nasal cavity are consistent with the hypothesis that excessive evaporation of mucus plays a key role in the pathophysiology of atrophic rhinitis, and it is concluded that the main goals of a surgery to treat atrophicrhinitis should be to restore the original surface area of the nose, to restored the physiological airflow distribution, and to create symmetric cavities.

TL;DR: This model will be used to evaluate the role of airflow patterns in determining the distribution of xenobiotically induced olfactory mucosal lesions and will provide comprehensive dosimetry models for extrapolating animal response data to humans.

TL;DR: It is concluded that target cell population size and sustained increases of cell proliferation in these populations, determined by differences in regional airflow-driven formaldehyde binding to DNA dose to these sites, can together account for the nonlinearity and site specificity of formaldehyde-induced nasal SCC in rats.