J
Julie Schmitt
Researcher at University of Strasbourg
Publications - 7
Citations - 399
Julie Schmitt is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Two-photon absorption & Quantum yield. The author has an hindex of 7, co-authored 7 publications receiving 356 citations. Previous affiliations of Julie Schmitt include Centre national de la recherche scientifique.
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Journal ArticleDOI
Diketopyrrolopyrrole-Porphyrin Conjugates with High Two-Photon Absorption and Singlet Oxygen Generation for Two-Photon Photodynamic Therapy†
Julie Schmitt,Valérie Heitz,Angélique Sour,Frédéric Bolze,Hussein Ftouni,Jean-François Nicoud,Lucia Flamigni,Barbara Ventura +7 more
TL;DR: Two new diketopyrrolopyrrole-porphyrin conjugates are reported as robust two-photon absorbing dyes with high two- photon absorption cross-sections within the therapeutic window, and for the first time the singlet-oxygen generation efficiency of dikonorphone-containing systems is investigated.
Journal ArticleDOI
A Theranostic Agent Combining a Two‐Photon‐Absorbing Photosensitizer for Photodynamic Therapy and a Gadolinium(III) Complex for MRI Detection
Julie Schmitt,Valérie Heitz,Angélique Sour,Frédéric Bolze,Pascal Kessler,Lucia Flamigni,Barbara Ventura,Célia S. Bonnet,Éva Tóth +8 more
TL;DR: The convergent synthesis and characterization of a potential theranostic agent, [DPP-ZnP-GdDOTA](-), which combines a diketopyrrolopyrrole-porphyrin component DPP- ZnP as a two-photon photosensitizer for photodynamic therapy (PDT) with a gadolinium(III) DOTA complex as a magnetic resonance imaging probe, is presented.
Journal ArticleDOI
Four Gadolinium(III) Complexes Appended to a Porphyrin: A Water-Soluble Molecular Theranostic Agent with Remarkable Relaxivity Suited for MRI Tracking of the Photosensitizer.
Angélique Sour,Sébastien Jenni,Ana Ortí-Suárez,Julie Schmitt,Valérie Heitz,Frédéric Bolze,Paulo Loureiro de Sousa,Chrystelle Po,Célia S. Bonnet,Agnès Pallier,Éva Tóth,Barbara Ventura +11 more
TL;DR: The ability of the gadolinium(III) conjugate to penetrate in cancer cells with low cytotoxicity and its phototoxicity on Hela cells was evaluated demonstrate the high potential of this conjugates as a theranostic agent for MRI and PDT.
Journal ArticleDOI
π-Extended diketopyrrolopyrrole–porphyrin arrays: one- and two-photon photophysical investigations and theoretical studies
Md. Mehboob Alam,Frédéric Bolze,Chantal Daniel,Lucia Flamigni,Christophe Gourlaouen,Valérie Heitz,Sébastien Jenni,Julie Schmitt,Angélique Sour,Barbara Ventura +9 more
TL;DR: A complete one- and two-photon spectroscopic and photophysical characterization of three diketopyrrolopyrrole-porphyrin conjugates shows a gradual broadening and bathochromic shift and a trend to lower energies, leading to remarkable NIR emission properties for the larger derivatives.
Journal ArticleDOI
A Porphyrin Dimer–GdDOTA Conjugate as a Theranostic Agent for One- and Two-Photon Photodynamic Therapy and MRI
Julie Schmitt,Sébastien Jenni,Angélique Sour,Valérie Heitz,Frédéric Bolze,Agnès Pallier,Célia S. Bonnet,Éva Tóth,Barbara Ventura +8 more
TL;DR: A molecular theranostic agent designed for photodynamic therapy (PDT) treatment in the near-infrared and for imaging tissue tumors with magnetic resonance imaging (MRI) is reported, which has shown very promising potential for PDT applications and the ability to be internalized in cells, thanks to its amphiphilic character.