J
Julien Zuber
Researcher at University of Paris
Publications - 146
Citations - 7203
Julien Zuber is an academic researcher from University of Paris. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 39, co-authored 129 publications receiving 5872 citations. Previous affiliations of Julien Zuber include Columbia University Medical Center & Boston Children's Hospital.
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Journal ArticleDOI
Genetics and Outcome of Atypical Hemolytic Uremic Syndrome: A Nationwide French Series Comparing Children and Adults
Véronique Frémeaux-Bacchi,Fadi Fakhouri,Arnaud Garnier,Frank Bienaimé,Marie-Agnès Dragon-Durey,Stéphanie Ngo,Bruno Moulin,Aude Servais,François Provôt,Lionel Rostaing,Stéphane Burtey,Patrick Niaudet,Georges Deschênes,Yvon Lebranchu,Julien Zuber,Chantal Loirat +15 more
TL;DR: Mortality rate was higher in children than adults with aHUS, but renal prognosis was worse in adults than children, and in children, the prognosis strongly depends on the genetic background.
Journal ArticleDOI
Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
TL;DR: A number of important issues require further study, including the appropriate duration of treatment according to an individual's genetic background and medical history, the optimal strategy to prevent post-transplantation recurrence of aHUS and a cost–efficacy analysis.
Journal ArticleDOI
Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
Aude Servais,Aude Servais,Laure-Hélène Noël,Lubka T. Roumenina,Moglie Le Quintrec,Stéphanie Ngo,Marie-Agnès Dragon-Durey,Marie-Agnès Dragon-Durey,Marie-Alice Macher,Julien Zuber,Julien Zuber,Alexandre Karras,François Provôt,Bruno Moulin,Jean-Pierre Grünfeld,Jean-Pierre Grünfeld,Patrick Niaudet,Patrick Niaudet,Philippe Lesavre,Philippe Lesavre,Véronique Frémeaux-Bacchi +20 more
TL;DR: A critical role of fluid-phase alternative pathway dysregulation in the pathogenesis of C3 glomerulopathies as well as in immune complex-mediated glomerular diseases is suggested.
Journal ArticleDOI
Haemolytic uraemic syndrome.
TL;DR: A specific mechanism-based treatment has been made available for patients affected by atypical haemolytic uraemic syndrome due to complement dysregulation, but such treatment is, however, still absent for several other disease types, including shiga toxin-induced haemologic syndrome.
Journal ArticleDOI
Outcome of Subclinical Antibody-Mediated Rejection in Kidney Transplant Recipients with Preformed Donor-Specific Antibodies
Alexandre Loupy,Caroline Suberbielle-Boissel,Gary S. Hill,Carmen Lefaucheur,Dany Anglicheau,Dany Anglicheau,Julien Zuber,Julien Zuber,F. Martinez,F. Martinez,Eric Thervet,Eric Thervet,Arnaud Mejean,Arnaud Mejean,Dominique Charron,J.-P. Duong Van Huyen,Patrick Bruneval,C. Legendre,C. Legendre,Dominique Nochy +19 more
TL;DR: Clinical relevance of subclinical antibody‐mediated rejection (SAMR) in a cohort of 54 DSA‐positive kidney transplant recipients receiving a deceased donor is described and screening biopsies may be useful to recognize patients more likely to develop SAMR.