J
Julio Sáez-Vásquez
Researcher at Centre national de la recherche scientifique
Publications - 52
Citations - 2149
Julio Sáez-Vásquez is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: RNA & Ribosomal RNA. The author has an hindex of 24, co-authored 48 publications receiving 1865 citations. Previous affiliations of Julio Sáez-Vásquez include University of Perpignan & Washington University in St. Louis.
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Journal ArticleDOI
Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis
Dominique Pontier,Galina Yahubyan,Danielle Vega,Agnès Bulski,Julio Sáez-Vásquez,Mohamed-Ali Hakimi,Silva Lerbs-Mache,Vincent Colot,Thierry Lagrange +8 more
TL;DR: The results imply the existence of a novel two-step mechanism in siRNA synthesis at highly methylated loci, with RNAPIVb being an essential component of a self-reinforcing loop coupling de novo DNA methylation to siRNA production.
Journal ArticleDOI
Characterization of AtNUC-L1 reveals a central role of nucleolin in nucleolus organization and silencing of AtNUC-L2 gene in Arabidopsis.
Frédéric Pontvianne,Isabel Matía,Julien Douet,Sylvette Tourmente,Francisco Javier Medina,Manuel Echeverria,Julio Sáez-Vásquez +6 more
TL;DR: This work is the first description of a higher eukaryotic organism with a disrupted nucleolin-like gene and defines a new role for nucleolin in nucleolus structure and rDNA chromatin organization.
Journal ArticleDOI
Nucleolin Is Required for DNA Methylation State and the Expression of rRNA Gene Variants in Arabidopsis thaliana
Frédéric Pontvianne,Mohamed Abou-Ellail,Julien Douet,Pascale Comella,Isabel Matía,Chinmayi Chandrasekhara,Anne Debures,Todd Blevins,Richard Cooke,Francisco Javier Medina,Sylvette Tourmente,Craig S. Pikaard,Julio Sáez-Vásquez +12 more
TL;DR: A novel mechanism for rRNA gene transcriptional regulation in which the nucleolin protein plays a major role in controlling active and repressed r RNA gene variants in Arabidopsis thaliana is revealed.
Journal ArticleDOI
Identification of Nucleolus-Associated Chromatin Domains Reveals a Role for the Nucleolus in 3D Organization of the A. thaliana Genome.
Frédéric Pontvianne,Frédéric Pontvianne,Frédéric Pontvianne,Marie-Christine Carpentier,Marie-Christine Carpentier,Nathalie Durut,Nathalie Durut,Veronika Pavlištová,Karin Jaške,Šárka Schořová,Hugues Parrinello,Marine Rohmer,Craig S. Pikaard,Craig S. Pikaard,Miloslava Fojtová,Jiří Fajkus,Julio Sáez-Vásquez,Julio Sáez-Vásquez +17 more
TL;DR: Roles for NUC1 and the nucleolus in the spatial organization of chromosomes as well as telomere maintenance are revealed in wild-type plants and null mutants.
Journal ArticleDOI
Sugar‐inducible expression of the nucleolin‐1 gene of Arabidopsis thaliana and its role in ribosome synthesis, growth and development
Hisae Kojima,Takamasa Suzuki,Takenori Kato,Ken Ichi Enomoto,Shusei Sato,Tomohiko Kato,Satoshi Tabata,Julio Sáez-Vásquez,Manuel Echeverria,Tsuyoshi Nakagawa,Sumie Ishiguro,Kenzo Nakamura +11 more
TL;DR: The AtNuc-L1 disruptant exhibited significantly reduced sugar-induced expression of ribosomal proteins (RPs) in Arabidopsis as mentioned in this paper, suggesting that RNA expression is involved in the sugar-inducible expression of RP genes.