J
Junfei Wei
Researcher at Baylor College of Medicine
Publications - 35
Citations - 788
Junfei Wei is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Antigen & Adjuvant. The author has an hindex of 14, co-authored 32 publications receiving 525 citations. Previous affiliations of Junfei Wei include Boston Children's Hospital & Capital Medical University.
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SARSCoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice.
Jeroen Pollet,Jeroen Pollet,Wen-Hsiang Chen,Wen-Hsiang Chen,Leroy Versteeg,Brian Keegan,Bin Zhan,Bin Zhan,Junfei Wei,Zhuyun Liu,Jungsoon Lee,Rahki Kundu,Rakesh Adhikari,Cristina Poveda,Maria Jose Villar,Ana Carolina de Araujo Leao,Joanne Altieri Rivera,Zoha Momin,Portia M. Gillespie,Jason T. Kimata,Ulrich Strych,Ulrich Strych,Peter J. Hotez,Maria Elena Bottazzi,Maria Elena Bottazzi,Maria Elena Bottazzi +25 more
TL;DR: In this article, a SARS-CoV-2 receptor-binding domain (RBD) protein, expressed at high levels in yeast (Pichia pastoris), was used as a suitable vaccine candidate against COVID-19.
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Trichinella spiralis paramyosin binds to C8 and C9 and protects the tissue-dwelling nematode from being attacked by host complement
Zhifei Zhang,Jing Yang,Junfei Wei,Yaping Yang,Xiaoqin Chen,Xi Zhao,Yuan Gu,Shijuan Cui,Xinping Zhu +8 more
TL;DR: These studies suggest that the outer membrane form of T. spiralis paramyosin plays an important role in the evasion of the host complement attack.
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Molecular cloning and characterization of heat shock protein 70 from Trichinella spiralis.
Shaohua Wang,Xinping Zhu,Yaping Yang,Jing Yang,Yuan Gu,Junfei Wei,Ran Hao,Pascal Boireau,Shijuan Cui +8 more
TL;DR: Recombinant Ts-Hsp70 could be recognized not only by trichinellosis patient sera, but also by T. spiralis- infected sera from rabbits, swine, and mice.
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Trichinella spiralis: Immune response and protective immunity elicited by recombinant paramyosin formulated with different adjuvants
Jing Yang,Yuan Gu,Yaping Yang,Junfei Wei,Shaohua Wang,Shijuan Cui,Jin Pan,Qiang Li,Xinping Zhu +8 more
TL;DR: The results revealed that immunization of BALB/c mice with rTs-Pmy formulated with either ISA206 or ISA720 triggered Th1 and Th2 immune responses similar to those produced by the conventional Freund's adjuvant formulation and also provided a similar level of protection against T. spiralis larval challenge.
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Protective Immunity against Trichinella spiralis Infection Induced by a Multi-Epitope Vaccine in a Murine Model
TL;DR: Results showed that a multi-epitope vaccine induced better protective immunity than an individual epitope and provided a feasible approach for developing a safer and more effective vaccine against trichinellosis.