J
Jürgen Peters
Researcher at University of Duisburg-Essen
Publications - 245
Citations - 8908
Jürgen Peters is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Ischemic preconditioning & Sepsis. The author has an hindex of 47, co-authored 243 publications receiving 8031 citations. Previous affiliations of Jürgen Peters include University of Düsseldorf.
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Increased circulating microRNA-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteria.
TL;DR: Increased miR-122 serum concentration supports the discrimination between infection and sepsis, is an early and independent risk factor for 30-day mortality, and improves the prognostic value of the SOFA-Score, suggesting a potential role for miR -122 in sepsi-related prediction models.
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Anticoagulant Effect of Sugammadex: Just an In Vitro Artifact.
Daniel Dirkmann,Martin W. Britten,Henning Pauling,Juliane Weidle,Lothar Volbracht,Klaus Görlinger,Jürgen Peters +6 more
TL;DR: Sugamadex significantly affects various coagulation assays, but this is explainable by an apparent phospholipid-binding effect, suggesting that Sugammadex`s anticoagulant effects are likely an in vitro artifact.
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Mitochondrial and Contractile Function of Human Right Atrial Tissue in Response to Remote Ischemic Conditioning
Petra Kleinbongard,Nilguen Gedik,Mücella Kirca,Leanda Stoian,Ulrich H. Frey,Afsaneh Zandi,Matthias Thielmann,Heinz Jakob,Jürgen Peters,Markus Kamler,Gerd Heusch +10 more
TL;DR: Cardioprotection by RIPC goes along with improved mitochondrial and contractile function of human right atrial tissue, and expression and phosphorylation of proteins were not different between RIPC and placebo.
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Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro-RNA signature in CABG patients.
Ulrich H. Frey,Ulrich H. Frey,Marina Klaassen,Crista Ochsenfarth,Crista Ochsenfarth,Florian Murke,Matthias Thielmann,Eva Kottenberg,Petra Kleinbongard,Stefanie Klenke,Andrea Engler,Gerd Heusch,Bernd Giebel,Jürgen Peters +13 more
TL;DR: The hypothesis that RIPC in anaesthetized patients undergoing coronary artery bypass (CABG) surgery results in the release of EVs from the ischaemic/reperfused arm into the blood stream harbouring cardioprotective miRNAs is tested.
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Spinal anaesthesia despite combined clopidogrel and aspirin therapy in a patient awaiting lung transplantation: effects of platelet transfusion on clotting tests.
Frank Herbstreit,Jürgen Peters +1 more
TL;DR: In selected patients, platelet transfusion may be appropriate to enable central neuraxial blockade when deemed necessary to enable anticoagulation in patients treated with newer antiplatelets.