J
Jürgen Schmidt
Researcher at Leibniz Association
Publications - 180
Citations - 5962
Jürgen Schmidt is an academic researcher from Leibniz Association. The author has contributed to research in topics: Mass spectrometry & Tandem mass spectrometry. The author has an hindex of 41, co-authored 178 publications receiving 5577 citations. Previous affiliations of Jürgen Schmidt include Leibniz Institute for Neurobiology & Martin Luther University of Halle-Wittenberg.
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Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase.
Stefan Irmler,Gudrun Schröder,Benoit St-Pierre,Nicholas P. Crouch,Michael Hotze,Jürgen Schmidt,Dieter Strack,Ulrich Matern,Joachim Schröder +8 more
TL;DR: The molecular characterization of CYP72A1 from Catharanthus roseus (Madagascar periwinkle) was described nearly a decade ago, but the enzyme function remained unknown, and it is shown by in situ hybridization and immunohistochemistry that the expression in immature leaves is epidermis-specific.
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FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis
Kathrin Schrick,Ulrike Mayer,Andrea Horrichs,Christine Kuhnt,Catherine Bellini,Jeff Dangl,Jürgen Schmidt,Gerd Jürgens +7 more
TL;DR: It is proposed that synthesis of sterol signals in addition to BRs is important in mediating regulated cell growth and organization during embryonic development and indicates a novel role for sterols in the embryogenesis of plants.
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Profiling of Arabidopsis Secondary Metabolites by Capillary Liquid Chromatography Coupled to Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry
Edda von Roepenack-Lahaye,Thomas Degenkolb,Michael Zerjeski,Mathias Franz,Udo Roth,Ludger A. Wessjohann,Jürgen Schmidt,Dierk Scheel,Stephan Clemens +8 more
TL;DR: A profiling approach that combines separation by capillary liquid chromatography with the high resolution, high sensitivity, and high mass accuracy of quadrupole time-of-flight mass spectrometry has the potential to significantly contribute to establishing the metabolome of Arabidopsis and other model systems.
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Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: tabersonine 16-hydroxylase.
Gudrun Schröder,Elke Unterbusch,Melanie Kaltenbach,Jürgen Schmidt,Dieter Strack,Vincenzo De Luca,Joachim Schröder +6 more
TL;DR: It is shown that T16H is induced in the suspension culture by light and the cloning of the cDNA is reported, and the possibility that the entire pathway to bisindoles can be expressed in suspension cultures is discussed.
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(r, s)- reticuline 7 o-methyltransferase and (r, s)- norcoclaurine 6-o-methyltransferase of papaver somniferum - cdna cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy
TL;DR: Steady-state kinetic measurements with one heterologously expressed enzyme and mass spectrometric analysis of the enzymatic products suggested that this unusual enzyme is capable of carrying through sequential O-methylations on the isoquinoline and on the benzyl moiety of several substrates.