J
Justin Chan
Researcher at Brown University
Publications - 2
Citations - 75
Justin Chan is an academic researcher from Brown University. The author has contributed to research in topics: IκB kinase & Signal transduction. The author has an hindex of 2, co-authored 2 publications receiving 72 citations.
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Journal ArticleDOI
Activation of IKK by thymosin α1 requires the TRAF6 signalling pathway
Ping Zhang,Justin Chan,Ana-Maria Dragoi,Xing Gong,Stanimir S. Ivanov,Zhi-Wei Li,Tsung-Hsien Chuang,Cynthia Tuthill,Yinsheng Wan,Michael Karin,Wen-Ming Chu +10 more
TL;DR: This study identifies T α1 as a unique activator of the TRAF6 signal pathway and provides a cohesive interpretation of the molecular basis of the therapeutic utility of Tα1.
Journal ArticleDOI
Signaling Pathways Leading to the Activation of IKK and MAPK by Thymosin α1
Xiao Peng,Ping Zhang,Xin Wang,Justin Chan,Mingwei Zhu,Meisheng Jiang,Cynthia Tuthill,Yinsheng Wan,Ana M. Dragoi,Wen-Ming Chu +9 more
TL;DR: It is found that Tα1 induces the production of interleukin‐6 (IL‐6), IL‐10, and IL‐12 in murine bone marrow‐derived macrophages (BMDMs) through IKK and MAPK pathways.