J
Justina N. Nwodo
Researcher at University of Nigeria, Nsukka
Publications - 7
Citations - 201
Justina N. Nwodo is an academic researcher from University of Nigeria, Nsukka. The author has contributed to research in topics: Virtual screening & Loranthaceae. The author has an hindex of 5, co-authored 7 publications receiving 162 citations. Previous affiliations of Justina N. Nwodo include Central Drug Research Institute.
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Molecular modeling of potential anticancer agents from African medicinal plants.
Fidele Ntie-Kang,Justina N. Nwodo,Akachukwu Ibezim,Conrad V. Simoben,Berin Karaman,Valery Fuh Ngwa,Wolfgang Sippl,Michael U. Adikwu,Luc Meva'a Mbaze +8 more
TL;DR: The results reveal that African medicinal plants could represent a good starting point for the discovery of anticancer drugs, and are made available for research groups working on virtual screening.
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Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part II: Alkaloids, Terpenoids and Flavonoids.
TL;DR: The potential of naturally occurring anti-cancer agents from African flora has been explored, with suggested modes of action, where such data is available, and three major compound classes are discussed which are: flavonoids, alkaloids and terpenoids.
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Metabolites from Combretum dolichopetalum and its associated endophytic fungus Nigrospora oryzae--Evidence for a metabolic partnership.
Philip F. Uzor,Weaam Ebrahim,Patience O. Osadebe,Justina N. Nwodo,Festus B. C. Okoye,Werner E.G. Müller,Wenhan Lin,Zhen Liu,Peter Proksch +8 more
TL;DR: Two new altersolanol derivative and 3, 3', 4-tri-O-methylellagic acid showed cytotoxicity against L5178Y mouse lymphoma cells with IC50 values of 9.4 and 29.0 μM, respectively, stressing the notion that some of the isolated plant metabolites may actually be of fungal origin.
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Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part I: Xanthones, Quinones, Steroids, Coumarins, Phenolics and other Classes of Compounds
TL;DR: The first part of this review series focuses on xanthones, quinones, steroids, coumarins, phenolics and other compound classes, while part II is focused on alkaloids, terpenoids, flavonoids.
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A novel sesquiterpene acid and an alkaloid from leaves of the Eastern Nigeria mistletoe, Loranthus micranthus with potent immunostimulatory activity on C57BL6 mice splenocytes and CD69 molecule.
EO Omeje,Patience O. Osadebe,Chukwuemeka S. Nworu,Justina N. Nwodo,Wilfred O Obonga,Akira Kawamura,Charles Okechukwu Esimone,Peter Proksch +7 more
TL;DR: Data suggest that the isolated compounds possess immunomodifying abilities, and may be responsible in part, for the immunostimulatory activities already established for the Eastern Nigeria mistletoes.