K
K. Gardiner
Researcher at Roosevelt Institute
Publications - 1
Citations - 1028
K. Gardiner is an academic researcher from Roosevelt Institute. The author has contributed to research in topics: Platelet disorder & Haploinsufficiency. The author has an hindex of 1, co-authored 1 publications receiving 975 citations.
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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
W.-J. Song,M. G. Sullivan,R. D. Legare,S Hutchings,Xiaolian Tan,Dubravka Kufrin,Janina Ratajczak,I. C. Resende,C. Haworth,R. Hock,Mignon L. Loh,C. Felix,Denis-Claude Roy,Lambert Busque,David M. Kurnit,Cheryl L. Willman,Alan M. Gewirtz,Nancy A. Speck,John H. Bushweller,Fugen Li,K. Gardiner,Mortimer Poncz,John M. Maris,D. G. Gilliland,D. G. Gilliland +24 more
TL;DR: The findings support a model for FPD/AML in which haploinsufficiency of CBFA2 causes an autosomal dominant congenital platelet defect and predisposes to the acquisition of additional mutations that cause leukaemia.