K.J.B. Lamers

TL;DR: Measurement of the combined local synthesis of antibodies against measles, rubella, and/or varicella zoster could represent a significant advance if it offers higher specificity (not sensitivity) for identifying chronic rather than acute inflammation.

TL;DR: The most sensitive method for detection of oligoclonal immunoglobulin bands isisoelectric focusing as discussed by the authors, where the same amounts ofIgG in parallel CSF and serum samples are used to reveal the IgG specific antibody staining.

TL;DR: S100b, GFAP, and NSE levels were significantly higher in patients who died or had a poor outcome 6 months post injury than in those who were alive or had good outcome, suggesting that determination of serum levels of glial and neuronal proteins may add to the clinical assessment of the primary damage and prediction of outcome after severe traumatic brain injury.

TL;DR: GFAP and S100B levels in serum are adjuncts to the assessment of brain damage after TBI and may enhance prognostication when combined with clinical variables.

TL;DR: Significantly higher MBP values were observed in patients with multiple sclerosis, cerebrovascular accident (CVA), metabolic disorder and infection and significantly higher values were demonstrated for S‐100 in CVA and for NSE in metabolic diseases.