C
Christian Sindic
Researcher at Cliniques Universitaires Saint-Luc
Publications - 174
Citations - 8141
Christian Sindic is an academic researcher from Cliniques Universitaires Saint-Luc. The author has contributed to research in topics: Multiple sclerosis & Antibody. The author has an hindex of 40, co-authored 174 publications receiving 7576 citations. Previous affiliations of Christian Sindic include Catholic University of Leuven & Université catholique de Louvain.
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Journal ArticleDOI
Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis
Robert J. Fox,David Miller,J. Theodore Phillips,Michael Hutchinson,Eva Havrdova,Mariko Kita,Minhua Yang,Kartik Raghupathi,Mark Novas,Marianne T. Sweetser,Vissia Viglietta,Katherine Dawson,Christian Sindic +12 more
TL;DR: In patients with relapsing-remitting multiple sclerosis, BG-12 (at both doses) and glatiramer acetate significantly reduced relapse rates and improved neuroradiologic outcomes relative to placebo.
Journal ArticleDOI
Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report.
Magnus Andersson,José C. Álvarez-Cermeño,Giorgio Bernardi,I. Cogato,Pam Fredman,Jette L. Frederiksen,Sten Fredrikson,Paolo Gallo,Lm. Grimaldi,M. Grønning,Geoffrey Keir,K.J.B. Lamers,Hans Link,A. Magalhaes,Ar. Massaro,Sten Öhman,Hansotto Reiber,Lars Rönnbäck,M. Schluep,E. Schuller,Christian Sindic,E J Thompson,Maria Trojano,U. Wurster +23 more
TL;DR: Measurement of the combined local synthesis of antibodies against measles, rubella, and/or varicella zoster could represent a significant advance if it offers higher specificity (not sensitivity) for identifying chronic rather than acute inflammation.
Journal ArticleDOI
Recommended Standard of Cerebrospinal Fluid Analysis in the Diagnosis of Multiple Sclerosis: A Consensus Statement
Mark S. Freedman,Edward J. Thompson,Florian Deisenhammer,Gavin Giovannoni,Guy Grimsley,Geoffrey Keir,Sten Öhman,Michael K. Racke,Mohammad K. Sharief,Christian Sindic,Finn Sellebjerg,Wallace W. Tourtellotte +11 more
TL;DR: In this article, the authors proposed new criteria for the diagnosis of multiple sclerosis (MS) using both clinical and paraclinical criteria, the latter involving information obtained from magnetic resonance imaging, evoked potentials, and cerebrospinal fluid (CSF) analysis.
Recommended Standard of Cerebrospinal Fluid Analysis in the Diagnosis of Multiple Sclerosis
Mark S. Freedman,Edward J. Thompson,Florian Deisenhammer,Gavin Giovannoni,Guy Grimsley,Geoffrey Keir,Sten Öhman,Michael K. Racke,Mohammad K. Sharief,Christian Sindic,Finn Sellebjerg,Wallace W. Tourtellotte +11 more
TL;DR: Recommendations for establishing a standard for the evaluation of CSF in patients suspected of having MS should greatly complement the new criteria in ensuring that a correct diagnosis of MS is being made.
Journal ArticleDOI
Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring
Ludwig Kappos,David W. Bates,Gilles Edan,Mefkure Eraksoy,Antonio Garcia-Merino,Nikolaos Grigoriadis,Hans Peter Hartung,Eva Havrdova,Jan Hillert,Reinhard Hohlfeld,Marcelo Kremenchutzky,Olivier Lyon-Caen,Ariel Miller,Carlo Pozzilli,Mads Ravnborg,Takahiko Saida,Christian Sindic,Karl Vass,David B. Clifford,Stephen L. Hauser,Eugene O. Major,Paul O'Connor,Howard L. Weiner,Michel Clanet,Ralf Gold,Hans H. Hirsch,Ernst W. Radü,Per Soelberg Sørensen,John King +28 more
TL;DR: This Review revisits and update previous recommendations on natalizumab for treatment of patients with RRMS, based on additional long-term follow-up of clinical studies and post-marketing observations, including appropriate patient selection and management recommendations.