Stimulated emission is the process fundamental to laser operation, thereby producing coherent photon output. Despite negatively charged nitrogen-vacancy (NV−) centres being discussed as a potential laser medium since the 1980s, there have been no definitive observations of stimulated emission from ensembles of NV− to date. Here we show both theoretical and experimental evidence for stimulated emission from NV− using light in the phonon sidebands around 700 nm. Furthermore, we show the transition from stimulated emission to photoionization as the stimulating laser wavelength is reduced from 700 to 620 nm. While lasing at the zero-phonon line is suppressed by ionization, our results open the possibility of diamond lasers based on NV− centres, tuneable over the phonon sideband. This broadens the applications of NV− magnetometers from single centre nanoscale sensors to a new generation of ultra-precise ensemble laser sensors, which exploit the contrast and signal amplification of a lasing system. Here Jeskeet al. show both theoretical and experimental evidence for stimulated emission from negatively charged nitrogen vacancy centres using light in the phonon sidebands around 700 nm, demonstrating its suitability as a laser medium.

/pdf/stimulated-emission-from-nitrogen-vacancy-centres-in-diamond-f111274026.pdf

Stimulated emission from nitrogen-vacancy centres in diamond

The family of oxide glasses is very wide and it is continuously developing. The rapid development of advanced and innovative glasses is under progress. Oxide glasses have a variety of applications in articles for daily use as well as in advanced technological fields such as X-ray protection, fibre glasses, optical instruments and lab glassware. Oxide glasses basically consist of network formers, such as borate, silicate, phosphate, borosilicate, borophosphate, and network modifiers such as alkali, alkaline earth and transition metals. In the present review article, Raman spectroscopy results for the structures of borate, silicate, phosphate, borosilicate, borophosphate, aluminosilicate, phosphosilicate, alumino-borosilicate and tellurite glasses are summarized.

A review of the structures of oxide glasses by Raman spectroscopy

The burgeoning field of nanophotonics has grown to be a major research area, primarily because of the ability to control and manipulate single quantum systems (emitters) and single photons on demand For many years studying nanophotonic phenomena was limited to traditional semiconductors (including silicon and GaAs) and experiments were carried out predominantly at cryogenic temperatures In the last decade, however, diamond has emerged as a new contender to study photonic phenomena at the nanoscale Offering plethora of quantum emitters that are optically active at room temperature and ambient conditions, diamond has been exploited to demonstrate super-resolution microscopy and realize entanglement, Purcell enhancement and other quantum and classical nanophotonic effects Elucidating the importance of diamond as a material, this review will highlight the recent achievements in the field of diamond nanophotonics, and convey a roadmap for future experiments and technological advancements

/pdf/diamond-nanophotonics-3gpmuladxc.pdf

Diamond Nanophotonics

This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its intact or modified form in indolocarbazoles, macrocyclic polyketides (cytochalasan alkaloids), the aporhoeadane alkaloids, meroterpenoids from Stachybotrys species and anthraquinone-type alkaloids. Concerning their biological activity, molecular structure and synthesis, we have limited this review to the most inspiring examples. Within different congeners, we have selected a few members and discussed the synthetic routes in more detail. The putative biosynthetic pathways of the presented isoindole alkaloids are described as well.

https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-9-243.pdf

The chemistry of isoindole natural products

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) and the inherent sensitivity of PET technique. A variety of radionuclides and mAbs have been exploited to develop immunoPET probes, which has been driven by the development and optimization of radiochemistry and conjugation strategies. In addition, tumor-targeting vectors with a short circulation time (e.g., Nanobody) or with an enhanced binding affinity (e.g., bispecific antibody) are being used to design novel immunoPET probes. Accordingly, several immunoPET probes, such as 89Zr-Df-pertuzumab and 89Zr-atezolizumab, have been successfully translated for clinical use. By noninvasively and dynamically revealing the expression of heterogeneous tumor antigens, immunoPET imaging is gradually changing the theranostic landscape of several types of malignancies. ImmunoPET is the method of choice for imaging specific tumor markers, immune cells, immune checkpoints, and inflammatory processes. Furthermore, the integration of immunoPET imaging in antibody drug development is of substantial significance because it provides pivotal information regarding antibody targeting abilities and distribution profiles. Herein, we present the latest immunoPET imaging strategies and their preclinical and clinical applications. We also emphasize current conjugation strategies that can be leveraged to develop next-generation immunoPET probes. Lastly, we discuss practical considerations to tune the development and translation of immunoPET imaging strategies.

ImmunoPET: Concept, Design, and Applications

We report a 790 nm pumped, Tm³⁺ doped ZBLAN glass buried waveguide laser that produces 47 mW at 1880 nm, with a 50% internal slope efficiency and an M² of 1.7. The waveguide cladding is defined by two overlapping rings created by femtosecond direct-writing of the glass, which results in the formation of a tubular depressed-index-cladding structure, and the laser resonator is defined by external dielectric mirrors. This is, to the best of our knowledge, the most efficient laser created in a glass host via femtosecond waveguide writing.

/pdf/fifty-percent-internal-slope-efficiency-femtosecond-direct-3cq4y9y13k.pdf

Fifty percent internal slope efficiency femtosecond direct-written Tm 3+:ZBLAN waveguide laser

M. R. Henderson, B. C. Gibson, H. Ebendorff-Heidepriem, K. Kuan , S. Afshar V., J. O. Orwa, I. Aharonovich ,S. Tomljenovic-Hanic, A. D. Greentree, S. Prawer, and T. M. Monro

Diamond in Tellurite Glass: a New Medium for Quantum Information

Heike Ebendorff-Heidepriem, Kevin Kuan, Michael R. Oermann, Kenton Knight, and Tanya M. Monro

Extruded tellurite glass and fibers with low OH content for mid-infrared applications

New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds.

http://www.im.ac.cn/UserFiles/File/2012/2012-05/5-Benzylidenerhodanine%20and.pdf

K. Kuan

Papers

Fifty percent internal slope efficiency femtosecond direct-written Tm 3+:ZBLAN waveguide laser

Diamond in Tellurite Glass: a New Medium for Quantum Information

Extruded tellurite glass and fibers with low OH content for mid-infrared applications

New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds.

5-benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials.