K
K. Papi Reddy
Researcher at Central Drug Research Institute
Publications - 22
Citations - 459
K. Papi Reddy is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Allyl alcohol & Phenylacetones. The author has an hindex of 8, co-authored 22 publications receiving 428 citations.
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Journal ArticleDOI
A simple and highly efficient method for the synthesis of chalcones by using borontrifluoride-etherate
TL;DR: In this paper, the synthesis of substituted acetophenones (2a-12a) with various aromatic aldehydes (1b-7b) in the presence of BF3-Et2O at room temperature gave chalcones in 75% yield.
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Antihyperglycemic and antidyslipidemic agent from Aegle marmelos
Tadigoppula Narender,Shweta Shweta,Priti Tiwari,K. Papi Reddy,Tanvir Khaliq,Philip Prathipati,Anju Puri,A. K. Srivastava,Ramesh Chander,S.C. Agarwal,Kanwal Raj +10 more
TL;DR: The reasonable mapping of compound 2 to validated pharmacophoric hypothesis and 3D QSAR model with an estimated activity suggest that the compound 2 might be a beta(3)-AR agonist.
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Synthesis of novel triterpenoid (lupeol) derivatives and their in vivo antihyperglycemic and antidyslipidemic activity.
TL;DR: The triterpenoid 4 lowered the blood glucose levels by 18.2% and 25.0% in sucrose challenged streptozotocin induced diabetic rats (STZ-S) model at the dose of 100mg/kg body weight.
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Peganine hydrochloride dihydrate an orally active antileishmanial agent.
Tanvir Khaliq,Pragya Misra,Swati Gupta,K. Papi Reddy,Ruchir Kant,P. R. Maulik,Anuradha Dube,Tadigoppula Narender +7 more
TL;DR: The compound 1 exhibited in-vitro activity against both extracellular promastigote as well as intracellular amastigotes residing within murine macrophages in Leishmania donovani, which resulted in the isolation of 1 as an antileishmanial agent.
Journal ArticleDOI
In vitro and in vivo anticancer activity of 2-deacetoxytaxinine J and synthesis of novel taxoids and their in vitro anticancer activity.
K. Papi Reddy,Hemant K. Bid,V. Lakshma Nayak,Preeti Chaudhary,J.P. Chaturvedi,K. R. Arya,Rituraj Konwar,Tadigoppula Narender +7 more
TL;DR: The structure-activity relationship studies indicated that the cinnamoyl group on C-5 and acetyl group onC-10 are essential for the anticancer activity.