T
Tadigoppula Narender
Researcher at Central Drug Research Institute
Publications - 124
Citations - 2512
Tadigoppula Narender is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Insulin resistance & GLUT4. The author has an hindex of 25, co-authored 117 publications receiving 2147 citations. Previous affiliations of Tadigoppula Narender include Scripps Research Institute & University of California, San Diego.
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Journal ArticleDOI
4-hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent
Tadigoppula Narender,Anju Puri,Shweta,Tanvir Khaliq,Rashmi Saxena,Geetika Bhatia,Ramesh Chandra +6 more
TL;DR: From the seeds of T. foenum-graecum an unusual amino acid, 4-hydroxyisoleucine 5, has been isolated, which significantly decreased the plasma triglyceride levels, accompanied by an increase in HDL-C/TC ratio in the dyslipidemic hamster model.
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A simple and highly efficient method for the synthesis of chalcones by using borontrifluoride-etherate
TL;DR: In this paper, the synthesis of substituted acetophenones (2a-12a) with various aromatic aldehydes (1b-7b) in the presence of BF3-Et2O at room temperature gave chalcones in 75% yield.
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Antihyperglycemic and antidyslipidemic agent from Aegle marmelos
Tadigoppula Narender,Shweta Shweta,Priti Tiwari,K. Papi Reddy,Tanvir Khaliq,Philip Prathipati,Anju Puri,A. K. Srivastava,Ramesh Chander,S.C. Agarwal,Kanwal Raj +10 more
TL;DR: The reasonable mapping of compound 2 to validated pharmacophoric hypothesis and 3D QSAR model with an estimated activity suggest that the compound 2 might be a beta(3)-AR agonist.
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A convenient and biogenetic type synthesis of few naturally occurring chromeno dihydrochalcones and their in vitro antileishmanial activity
TL;DR: The strategy to conveniently synthesize naturally occurring chromeno dihydrochalcones by biogenetic type pyridine or Amberlyst-15 catalyzed chromenylation of dihydropyranes and in vitro antileishmanial activity of chromenoDihydro Chalcones and their intermediates is reported.
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Prenylated chalcones isolated from Crotalaria genus inhibits in vitro growth of the human malaria parasite Plasmodium falciparum.
TL;DR: In vitro antimalarial activity of crotaorixin as well as few prenylated chalcones isolated from C. medicagenia and C. ramosissima were evaluated at three concentrations against Plasmodium falciparum (Strain NF-54).