K
K. Richard Bruckdorfer
Researcher at University College London
Publications - 61
Citations - 2752
K. Richard Bruckdorfer is an academic researcher from University College London. The author has contributed to research in topics: Ascorbic acid & Peroxynitrite. The author has an hindex of 22, co-authored 61 publications receiving 2625 citations. Previous affiliations of K. Richard Bruckdorfer include University of London & University College Hospital.
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Journal ArticleDOI
Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?
TL;DR: It is difficult to see why a combination of vitamin C with other vitamins should reduce its protective effects, if they were real, and in the case of other antioxidant vitamins, notably vitamin E, results of single-factor trials and observational studies show a similar discordance to those seen in the figure for vitamin C.
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Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis
TL;DR: Vitamin C has antiinflammatory effects and is associated with lower endothelial dysfunction in men with no history of cardiovascular disease or diabetes, and shows inverse associations with both fibrinogen concentrations and blood viscosity.
Journal ArticleDOI
The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans
Ananth S. Pannala,Ali R. Mani,Jeremy P. E. Spencer,Vernon O. Skinner,K. Richard Bruckdorfer,Kevin P. Moore,Catherine Rice-Evans +6 more
TL;DR: While urinary, salivary, and plasma nitrate concentrations increased between 4- and 7-fold, a significant increase in nitrite was only detected in saliva (7-fold).
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Anticoagulant and antiplatelet agents: their clinical and device application(s) together with usages to engineer surfaces.
Asmeret G. Kidane,Henryk J. Salacinski,Alok Tiwari,K. Richard Bruckdorfer,Alexander M. Seifalian +4 more
TL;DR: The current state of the art of antiplatelet and anticoagulant therapy is reviewed in light of its potential clinical efficacy and the usage of these agents more specifically heparin, heparan, hirudin, and coumarin in the development of more biocompatible scaffolds for tissue engineering is looked at.
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Ghrelin Can Bind to a Species of High Density Lipoprotein Associated with Paraoxonase
Nicholas J. Beaumont,Vernon O. Skinner,Tricia Tan,Bala Ramesh,Dominic J. Byrne,Gavin MacColl,Jeff N. Keen,Pierre M. Bouloux,Dimitri P. Mikhailidis,K. Richard Bruckdorfer,Mark Vanderpump,Kaila S. Srai +11 more
TL;DR: It is shown that an immobilized form of ghrelin specifically binds a species of high density lipoprotein associated with the plasma esterase, paraoxonase, and clusterin, which links the orexigenic peptide hormone gh Relin to lipid transport and metabolism.