K
K. Thong Wong
Researcher at University of Malaya
Publications - 6
Citations - 1087
K. Thong Wong is an academic researcher from University of Malaya. The author has contributed to research in topics: Virus & Mesocricetus. The author has an hindex of 6, co-authored 6 publications receiving 1027 citations.
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Journal ArticleDOI
Localization of Dengue Virus in Naturally Infected Human Tissues, by Immunohistochemistry and In Situ Hybridization
TL;DR: Tissue specimens from patients with serologically or virologically confirmed dengue infections are studied by immunohistochemistry (IHC) and in situ hybridization (ISH), to localize viral antigen and RNA, respectively.
Journal ArticleDOI
A golden hamster model for human acute Nipah virus infection
K. Thong Wong,Isabelle Grosjean,Christine Brisson,Barissa Blanquier,Michelle Fèvre-Montange,Arlette Bernard,Philippe Loth,Marie Claude Georges-Courbot,Michelle Chevallier,Hideo Akaoka,Philippe Marianneau,Sai Kit Lam,T. Fabian Wild,Vincent Deubel +13 more
TL;DR: A golden hamster (Mesocricetus auratus) model is proposed as a suitable model for further studies including pathogenesis studies, anti-viral drug testing, and vaccine development against acute Nipah infection.
Animal Model A Golden Hamster Model for Human Acute Nipah Virus Infection
K. Thong Wong,Isabelle Grosjean,Christine Brisson,Barissa Blanquier,Michelle Fevre-Montange,Arlette Bernard,Philippe Loth,Marie-Claude Georges-Courbot,Michelle Chevallier,Hideo Akaoka,Philippe Marianneau,Sai Kit Lam,T. Fabian Wild,Vincent Deubel +13 more
TL;DR: Wong et al. as mentioned in this paper described a golden hamster (Mesocricetus auratus) model that appears to reproduce the pathology and pathogenesis of acute human Nipah infection.
Journal ArticleDOI
Acute Hendra virus infection: Analysis of the pathogenesis and passive antibody protection in the hamster model.
Vanessa Guillaume,K. Thong Wong,Ren Yih Looi,Marie-Claude Georges-Courbot,Laura Barrot,Robin Buckland,Robin Buckland,Robin Buckland,T. Fabian Wild,T. Fabian Wild,T. Fabian Wild,Branka Horvat,Branka Horvat,Branka Horvat +13 more
TL;DR: Golden hamster presents a convenient novel animal model to study HeV infection, opening new perspectives to evaluate vaccine and therapeutic approaches against this emergent infectious disease, and reveals the similarities between HeV and NiV pathogenesis.
Journal ArticleDOI
Experimental infection of squirrel monkeys with Nipah virus
Philippe Marianneau,Vanessa Guillaume,K. Thong Wong,Munisamy Badmanathan,Ren Yih Looi,Séverine Murri,Philippe Loth,Noël Tordo,T. Fabian Wild,Branka Horvat,Hugues Contamin +10 more
TL;DR: Infection of squirrel monkeys with Nipah virus determined the monkeys’ suitability for use as primate models in preclinical testing of preventive and therapeutic treatments.