K. Vuorio

TL;DR: Alterations in striatal presynaptic dopamine function may constitute a part of disrupted neural circuits that predispose to schizophrenic psychosis.

TL;DR: The major finding in this study is that depressive symptoms in neuroleptic-naive first-admission schizophrenia are associated with low presynaptic dopamine function, which appears to be hemisphere-related and may have drug-treatment implications, e.g., in prediction of response to D2 receptor blocking antipsychotic drugs.

TL;DR: There are no general changes in D2 dopamine receptor Bmax or Kd values in neuroleptic-naive schizophrenics, but there may be a subgroup of patients with aberrant striatal D 2 dopamine receptor characteristics in vivo.

TL;DR: The background, rationale, set-up and first results of the Finnish API study are presented, whose aim was to investigate the use of a psychotherapeutically oriented and familycentred treatment model for acute psychosis in different treatment settings, and especially the role of neuroleptic drug treatment when working along the principles of the integrated treatment model.

TL;DR: Eight patients treated at the Psychiatric Department of the University Central Hospital of Turku (UCHT) Finland who all had as a common feature an unfounded fear of AIDS are described, a new problem especially for general hospital psychiatry.