K
K. Welvaart
Researcher at Leiden University
Publications - 23
Citations - 4181
K. Welvaart is an academic researcher from Leiden University. The author has contributed to research in topics: Cancer & Radiation therapy. The author has an hindex of 15, co-authored 23 publications receiving 4041 citations.
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Journal ArticleDOI
Extended Lymph-Node Dissection for Gastric Cancer
J J Bonenkamp,John J. Hermans,M. Sasako,C.J.H. van de Velde,K. Welvaart,I. Songun,S. Meyer,JThM Plukker,P. van Elk,Huug Obertop,D. J. Gouma,J. J. B. van Lanschot,C.W. Taat,P. W. de Graaf,M.F. von Meyenfeldt,H. W. Tilanus +15 more
TL;DR: The results in Dutch patients do not support the routine use of D2 lymph-node dissection in patients with gastric cancer, as recommended by the Japanese medical community.
Journal ArticleDOI
Randomised comparison of morbidity after D1 and D2 dissection for gastric cancer in 996 Dutch patients
J. J. Bonenkamp,I. Songun,K. Welvaart,C.J.H. van de Velde,Jo Hermans,M. Sasako,JThM Plukker,P. van Elk,Huug Obertop,Dirk J. Gouma,C.W. Taat,J. J. B. van Lanschot,S. Meyer,P. W. de Graaf,M.F. von Meyenfeldt,H. W. Tilanus +15 more
TL;DR: Morbidity and mortality differences persisted in almost all subgroup analyses, and D2 dissection should not be used as standard treatment for western patients.
Journal ArticleDOI
Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial
Henk H. Hartgrink,C.J.H. van de Velde,Hein Putter,Johannes J. Bonenkamp,E. Klein Kranenbarg,I. Songun,K. Welvaart,J.H.J.M. van Krieken,Sybren L. Meijer,J. T. Plukker,P. van Elk,Huug Obertop,D. J. Gouma,J. J. B. van Lanschot,C.W. Taat,P. W. de Graaf,M.F. von Meyenfeldt,H. W. Tilanus,M. Sasako +18 more
TL;DR: Overall, extended lymph node dissection as defined in this study generated no long-term survival benefit, and the associated higher postoperative mortality offsets its long- term effect in survival.
Journal Article
Prognostic relevance of plasminogen activators and their inhibitors in colorectal cancer
S. Ganesh,Cornelis F. M. Sier,Gerrit Griffioen,H. J. M. Vloedgraven,A.C. de Boer,K. Welvaart,C.J.H. van de Velde,J.H.J.M. van Krieken,Jan H. Verheijen,Cornelis B.H.W. Lamers,H. W. Verspaget +10 more
TL;DR: The prognostic value of t-PA antigen and activity in normal mucosa, the antigen ratio of u-PA in carcinoma (C) and t- PA in corresponding normal (N) mucosa), and PAI-2 antigen in carcinomas was found to be independent from clinicopathological parameters by multivariate analyses.
Journal ArticleDOI
The effect of radiotherapy on dysphagia and survival in patients with esophageal cancer.
TL;DR: A group of 127 patients with esophageal cancer treated with radiotherapy at different dose levels was retrospectively analysed and it was found that 70.5% of the patients showed improvement of dysphagia and that 54% remained palliated with respect to food passage until their death.