K
Kai Dong
Researcher at Second Military Medical University
Publications - 2
Citations - 35
Kai Dong is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Thermogenesis & White adipose tissue. The author has an hindex of 1, co-authored 2 publications receiving 7 citations.
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The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
Gang Wei,Honglin Sun,Kai Dong,Libing Hu,Qi Wang,Qian Zhuang,Yan Zhu,Xianjing Zhang,Yaodi Shao,Huiru Tang,Zhenfei Li,Suzhen Chen,Junxi Lu,Yibing Wang,Xinxin Gan,Tao P. Zhong,Dingkun Gui,Xiaoyong Hu,Linhui Wang,Junli Liu +19 more
TL;DR: In this article, a bi-directional communication between ccRCC cells and perinephric adipose tissue (PAT) was described, and it was shown that if this cross-communication was short circuited by the pharmacological suppression of adipocyte browning via H89 or KT5720, the anti-tumor efficacy of the TKI, sunitinib, was enhanced.
Journal ArticleDOI
Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning
TL;DR: Results clearly show that as an effective BAT (as well as beige cells) activator, indirubin may have a protective effect on the prevention and treatment of obesity and its complications.