K
Kai-Wen Huang
Researcher at National Taiwan University
Publications - 109
Citations - 1770
Kai-Wen Huang is an academic researcher from National Taiwan University. The author has contributed to research in topics: Hepatocellular carcinoma & Medicine. The author has an hindex of 20, co-authored 100 publications receiving 1302 citations. Previous affiliations of Kai-Wen Huang include National Taiwan Normal University.
Papers
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Journal ArticleDOI
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo
Vikash Reebye,Pål Sætrom,Paul J. Mintz,Kai-Wen Huang,Piotr Swiderski,Ling Peng,Cheng Liu,Xiaoxuan Liu,Steen Lindkær-Jensen,Dimitris Zacharoulis,Nikolaos Kostomitsopoulos,Noriyuki Kasahara,Joanna Nicholls,Long R. Jiao,Madhava Pai,Duncan Spalding,Malkhaz Mizandari,Tinatin Chikovani,Mohamed Emara,Abdelali Haoudi,Donald A. Tomalia,John J. Rossi,Nagy A. Habib +22 more
TL;DR: A novel injectable saRNA‐oligonucleotide that enhances C/EBPα expression successfully reduces tumor burden and simultaneously improves liver function in a clinically relevant liver cirrhosis/HCC model.
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Transient Elastography to Assess Hepatic Fibrosis in Hemodialysis Chronic Hepatitis C Patients
Chen-Hua Liu,Cheng-Chao Liang,Kai-Wen Huang,Chun-Jen Liu,Shih-I Chen,Jou-Wei Lin,Peir-Haur Hung,Hung-Bin Tsai,Ming-Yang Lai,Pei-Jer Chen,Jun-Herng Chen,Ding-Shinn Chen,Jia-Horng Kao +12 more
TL;DR: TE is superior to APRI in assessing the severity of hepatic fibrosis and can substantially decrease the need of staging PLB in hemodialysis patients with CHC.
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Irreversible electroporation in locally advanced pancreatic cancer: A call for standardization of energy delivery.
Robert C.G. Martin,Alan North Durham,Marc G. Besselink,David A. Iannitti,Matthew J. Weiss,Christopher L. Wolfgang,Kai-Wen Huang +6 more
TL;DR: Standardization of IRE technique and protocols is expected to improve safety, lead to reproducible outcomes, and facilitate further research into IRE.
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Time-Evolution contrast of target MRI using high-stability antibody functionalized magnetic nanoparticles: an animal model
Kai-Wen Huang,S. Y. Yang,Herng-Er Horng,Jen Jie Chieh,Hsin Hsien Chen,Chung-Chih Wu,J. H. Chen,I. T. Lin,C. C. Yang,Hong-Chang Yang +9 more
TL;DR: The observing time window for the specific labeling of tumors with antibody functionalized magnetic nanoparticles was found to be 20 hours after injecting biofunctionalized magnets into mice, and the long-term darkness of tumor magnetic-resonance image is due to the specific anchoring of antibodies at tumor.
Journal ArticleDOI
Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth
Sorah Yoon,Kai-Wen Huang,Vikash Reebye,Duncan Spalding,Teresa M. Przytycka,Yijie Wang,Piotr Swiderski,Lin Li,Brian Armstrong,Isabella Reccia,Dimitris Zacharoulis,Konstantinos Dimas,Tomokazu Kusano,John E. Shively,Nagy A. Habib,John J. Rossi,John J. Rossi +16 more
TL;DR: The conjugation of cytotoxic drugs to an aptamer previously described by this group, the pancreatic cancer RNA aptamer P19, is reported on, suggesting that this approach may be useful in decreasing cytot toxic side effects in non-tumoral tissue.