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Kanneboyina Nagaraju

Researcher at Binghamton University

Publications -  189
Citations -  9970

Kanneboyina Nagaraju is an academic researcher from Binghamton University. The author has contributed to research in topics: Duchenne muscular dystrophy & Skeletal muscle. The author has an hindex of 52, co-authored 181 publications receiving 8793 citations. Previous affiliations of Kanneboyina Nagaraju include Children's National Medical Center & Johns Hopkins University.

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Vamorolone, a dissociative steroidal compound, reduces collagen antibody-induced joint damage and inflammation when administered after disease onset

TL;DR: It is found that vamorolone treatment led to a reduction of several disease parameters including disease score, joint inflammation, and the presence of pro-inflammatory mediators to a degree similar of that observed with prednisolonetreatment.
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Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy.

TL;DR: In this paper, the turnover dynamics of restored dystrophin and dystroglycan complex (DGC) proteins in mdx mice after exon skipping therapy, compared to those dynamics in wild type mice, using a targeted, highly-reproducible and sensitive, in vivo stable isotope labeling mass spectrometry approach in multiple muscle tissues.
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Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne.

TL;DR: A number of biomarkers, both known and novel, which may be related to either the mechanisms of muscle injury in DMD or prednisolone treatment are reported, including peaks identified as biliverdin and hypusine.