K
Kaoru Umehara
Researcher at University of Shizuoka
Publications - 85
Citations - 2596
Kaoru Umehara is an academic researcher from University of Shizuoka. The author has contributed to research in topics: Glycoside & Melanin. The author has an hindex of 29, co-authored 83 publications receiving 2293 citations. Previous affiliations of Kaoru Umehara include Tokyo Medical and Dental University & Tohoku Pharmaceutical University.
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Journal ArticleDOI
Cell Differentiation-Inducing Diterpenes from Andrographis paniculata NEES
Takakuni Matsuda,Masanori Kuroyanagi,Satoko Sugiyama,Kaoru Umehara,Akira Ueno,Kozaburo Nishi +5 more
TL;DR: The methanol extract of the aerial part of Andrographis paniculata Nees showed potent cell differentiation-inducing activity on mouse myeloid leukemia (M1) cells and four new diterpene dimers were isolated along with six known compounds.
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Green tea polyphenols: novel and potent inhibitors of squalene epoxidase.
Ikuro Abe,Takahiro Seki,Kaoru Umehara,Toshio Miyase,Hiroshi Noguchi,Jun Sakakibara,Teruo Ono +6 more
TL;DR: It was demonstrated for the first time that the cholesterol lowering effect of green tea may be attributed to their potent SE inhibition activities, and that EGCG inhibited SE in noncompetitive, and non-time-dependent manner.
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Sesquiterpene Lactones from Cichorium endivia L. and C. intybus L. and Cytotoxic Activity
TL;DR: Four new sesquiterpene lactones have been isolated from Cichorium endivia L. and C. intybus L., together with nine known sesQUiterpenes lactones, and the structures of the new compounds were established on the basis of chemical and spectral data.
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Studies on the constituents of leaves of Citrus unshiu Marcov.
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Phytoestrogens from Aspalathus linearis.
TL;DR: From the leaves of Aspalathus linearis, 24 known compounds and a new one, aspalalinin, were isolated and the structures of the compounds were determined mainly based on spectral evidence.