K
Karen C. Stokes
Researcher at North Carolina State University
Publications - 1
Citations - 750
Karen C. Stokes is an academic researcher from North Carolina State University. The author has contributed to research in topics: Oxidative stress & PBT2. The author has an hindex of 1, co-authored 1 publications receiving 726 citations.
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Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity CORRELATION WITH CELL-FREE HYDROGEN PEROXIDE PRODUCTION AND METAL REDUCTION
Xudong Huang,Math P. Cuajungco,Craig S. Atwood,Mariana A. Hartshorn,Joel D. A. Tyndall,Graeme R. Hanson,Karen C. Stokes,Michael C. Leopold,Gerd Multhaup,Lee E. Goldstein,Richard C. Scarpa,Aleister J. Saunders,James Lim,Robert D. Moir,Charles G. Glabe,Edmond F. Bowden,Colin L. Masters,David P. Fairlie,Rudolph E. Tanzi,Ashley I. Bush +19 more
TL;DR: It is reported that Cu(II) markedly potentiates the neurotoxicity exhibited by Abeta in cell culture, suggesting that certain redox active metal ions may be important in exacerbating and perhaps facilitating Abeta-mediated oxidative damage in Alzheimer's disease.