K
Karen R. Cleary
Researcher at University of Texas MD Anderson Cancer Center
Publications - 158
Citations - 20952
Karen R. Cleary is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Adenocarcinoma & Metastasis. The author has an hindex of 67, co-authored 158 publications receiving 20453 citations. Previous affiliations of Karen R. Cleary include University of Texas Health Science Center at Houston & University of Florida.
Papers
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Direct intratumoral injection of a novel collagen matrix gel and cisplatin effectively controls experimental liver tumors
S. A. Curley,George M. Fuhrman,Z. H. Siddik,B. S. Davidson,Karen R. Cleary,Douglas M. Cromeens +5 more
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Hepatic arterial infusion of verapamil and doxorubicin with complete hepatic venous isolation and extracorporeal chemofiltration: pharmacological evaluation of reduction in systemic drug exposure and assessment of hepatic toxicity
George M. Fuhrman,Douglas M. Cromeens,Robert A. Newman,Karen R. Cleary,Cesar H. Carrasco,Kenneth C. Wright,S. Guercio,A. Guercio,S. A. Curley +8 more
TL;DR: Results of this study indicate that hepatic arterial infusion of verapamil and doxorubicin, in an attempt to improve treatment response in unresectable liver tumours expressing the multidrug resistance phenotype, may not be tolerated by patients with limited hepatic reserve.
Journal ArticleDOI
Human cell line from an adenocarcinoma of the ampulla of vater
Marsha L. Frazier,Nicolas Brown,Sen Pathak,Bruce Mackay,Karen R. Cleary,Matilde Olive,David R. Byrd,Douglas B. Evans,Bernard Levin +8 more
TL;DR: The MDAAmp-7 cell line was cultured from a metastatic abdominal implant that arose from the primary adenocarcinoma of the ampulla of Vater, and displayed a spectrum ranging from well-differentiated glandular structures to small clusters of cells and highly anaplastic single cells with occasional signet-ring configuration transmitted through the museularis propria of the duodenum into peripanereatic adipose tissue.
Book ChapterDOI
P08 01 sp – pre-treatment tumor cell kinetics in patients with advanced primary and recurrent rectal adenocarcinomas are associated with treatment response to pre-operative chemo/radiotherapy (cxrt)
Tyvin A. Rich,Marvin L. Meistrich,Nicholas H. A. Terry,A. White,L. Peters,Karen R. Cleary,Jaffer A. Ajani,David M. Ota +7 more
Journal ArticleDOI
Regional DNA content heterogeneity in colonic adenocarcinoma: prognostic significance in patients with liver metastases.
TL;DR: Examining the DNA ploidy pattern in tissue blocks from 25 primary colon adenocarcinomas and their lymph node and liver metastases concluded that three of eight patients in the diploid group remain free of disease, while all 16 patients with aneuploid cell populations have died of recurrent disease.