K
Karen R. Cleary
Researcher at University of Texas MD Anderson Cancer Center
Publications - 158
Citations - 20952
Karen R. Cleary is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Adenocarcinoma & Metastasis. The author has an hindex of 67, co-authored 158 publications receiving 20453 citations. Previous affiliations of Karen R. Cleary include University of Texas Health Science Center at Houston & University of Florida.
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Journal ArticleDOI
Prognostic factors in esophageal squamous carcinoma. A study of histologic features, blood group expression, and DNA ploidy.
S. S. Robey-Cafferty,Adel K. El-Naggar,Aysegul A. Sahin,Janet M. Bruner,Jae Y. Ro,Karen R. Cleary +5 more
TL;DR: The degree of differentiation and stage of the tumors were the only two independently significant prognostic indicators in this study.
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Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma.
TL;DR: It is suggested that the production of bFGF by pancreatic cancer cells induces ductal and stromal hyperplasia of the pancreas and significant upregulation of basic fibroblast growth factor mRNA expression in adjacent tumor cells.
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Expression of interferon-β is associated with growth arrest of murine and human epidermal cells
Diane R. Bielenberg,Marya F. McCarty,Corazon D. Bucana,Stuart H. Yuspa,David Morgan,Jeffrey M. Arbeit,Lee M. Ellis,Karen R. Cleary,Isaiah J. Fidler +8 more
TL;DR: Data indicate that interferon-β is produced by growth-arrested, terminally differentiated keratinocytes, a regulator of cell replication and function, including invasion and induction of angiogenesis.
Journal Article
Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues.
Tatsuro Irimura,Debora A. Carlson,Janet E. Price,Takao Yamori,Raffaella Giavazzi,David M. Ota,Karen R. Cleary +6 more
TL;DR: The expression in liver metastases derived from parental as well as metastatic cells was higher than the primary tumor growing in the spleen of the same mouse, indicating that the levels of Mr 900,000 sialoglycoprotein were regulated by intrinsic and environmental factors.
Journal Article
Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells.
Tatsuro Irimura,Andrew M. McIsaac,Debora A. Carlson,Masato Yagita,Elizabeth A. Grimm,David G. Menter,David M. Ota,Karen R. Cleary +7 more
TL;DR: The colon carcinoma cells treated with the conditioned medium and producing increased amounts of high-molecular-weight sialoglycoproteins were less sensitive to the cytolytic effects of recombinant interleukin 2-activated human peripheral blood lymphocytes than untreated cells were.