scispace - formally typeset
K

Karen R. Cleary

Researcher at University of Texas MD Anderson Cancer Center

Publications -  158
Citations -  20952

Karen R. Cleary is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Adenocarcinoma & Metastasis. The author has an hindex of 67, co-authored 158 publications receiving 20453 citations. Previous affiliations of Karen R. Cleary include University of Texas Health Science Center at Houston & University of Florida.

Papers
More filters
Journal ArticleDOI

Prognostic factors in esophageal squamous carcinoma. A study of histologic features, blood group expression, and DNA ploidy.

TL;DR: The degree of differentiation and stage of the tumors were the only two independently significant prognostic indicators in this study.
Journal ArticleDOI

Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma.

TL;DR: It is suggested that the production of bFGF by pancreatic cancer cells induces ductal and stromal hyperplasia of the pancreas and significant upregulation of basic fibroblast growth factor mRNA expression in adjacent tumor cells.
Journal ArticleDOI

Expression of interferon-β is associated with growth arrest of murine and human epidermal cells

TL;DR: Data indicate that interferon-β is produced by growth-arrested, terminally differentiated keratinocytes, a regulator of cell replication and function, including invasion and induction of angiogenesis.
Journal Article

Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues.

TL;DR: The expression in liver metastases derived from parental as well as metastatic cells was higher than the primary tumor growing in the spleen of the same mouse, indicating that the levels of Mr 900,000 sialoglycoprotein were regulated by intrinsic and environmental factors.
Journal Article

Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells.

TL;DR: The colon carcinoma cells treated with the conditioned medium and producing increased amounts of high-molecular-weight sialoglycoproteins were less sensitive to the cytolytic effects of recombinant interleukin 2-activated human peripheral blood lymphocytes than untreated cells were.