K
Karin D. Rodland
Researcher at Pacific Northwest National Laboratory
Publications - 166
Citations - 11000
Karin D. Rodland is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Proteomics & Cancer. The author has an hindex of 46, co-authored 152 publications receiving 8139 citations. Previous affiliations of Karin D. Rodland include Reed College & Oregon Health & Science University.
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The pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease
TL;DR: It is concluded that the pilus‐induced Ca2+ flux increases the amount of Lamp1 that is cleavable by the IgA1 protease, and surface Lamp1 is cleaved by IgA 1 protease secreted by adherent bacteria.
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Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism.
TL;DR: The data suggest that activation of pkC is an essential component of the downstream events responsible for the stimulation of cell proliferation and anchorage-independent growth in Rat-1 cells exposed to Et-1.
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The clinical impact of recent advances in LC-MS for cancer biomarker discovery and verification
Hui Wang,Tujin Shi,Wei-Jun Qian,Tao Liu,Jacob Kagan,Sudhir Srivastava,Richard D. Smith,Karin D. Rodland,David G. Camp +8 more
TL;DR: The recent advances in LC–MS and its applications in cancer biomarker discovery and quantification, along with the potentials, limitations and future perspectives are reviewed.
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Proliferation of Rhesus Ovarian Surface Epithelial Cells in Culture: Lack of Mitogenic Response to Steroid or Gonadotropic Hormones
TL;DR: It is found that concentrations of progesterone and estrogen normally present in follicles just before ovulation significantly decrease the number of mitotically active rhesus macaque OSE cells as determined by PCNA labeling, total cell count, and (3)H-thymidine uptake, whereas lower steroid concentrations have no effect.
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Analysis of Serum Total and Free PSA Using Immunoaffinity Depletion Coupled to SRM: Correlation with Clinical Immunoassay Tests
Tao Liu,Mahmud Hossain,Athena A. Schepmoes,Thomas L. Fillmore,Lori J. Sokoll,Scott R. Kronewitter,Grant Izmirlian,Tujin Shi,Wei-Jun Qian,Robin J. Leach,Ian M. Thompson,Daniel W. Chan,Richard D. Smith,Jacob Kagan,Sudhir Srivastava,Karin D. Rodland,David G. Camp +16 more
TL;DR: The development of immunoaffinity depletion-based workflows and SRM-MS assays that enable sensitive and accurate quantification of total and free prostate-specific antigen (PSA) in serum without the requirement for specific PSA antibodies are reported for the first time.