Karin Hahnke

TL;DR: It is determined that YhaM is an unspecific enzyme that trims a few nucleotides and targets the majority of transcript ends, generated either by transcription termination or by endonucleolytic activity, which sheds light on the very distinct features of S. pyogenes 3′-to-5′ exoRNases.

TL;DR: It is found that FcRn expression maintains homeostatic IgG levels in lung and leads to preferential secretion of low-affinity IgG ligands into the lumen, which sheds light on the role of mucosal IgG in immune responses in the lung during homeostasis and bacterial disease.

TL;DR: It is shown that stripping of commercial in situ arrays is feasible and that reuse of stripped arrays gave similar results compared to unused ones, and that the stripping procedure does not significantly influence data quality derived from post-primary hybridizations.

TL;DR: It is demonstrated for the first time that RNase Y processing of an mRNA target requires the presence of a G, which is essential for the processing of the 5′ untranslated region of speB mRNA 5′ UTR byRNase Y.

TL;DR: In the intestinal mucosa, conventional CD8αβ+ T cells lack NKR expression and thereby lose responsiveness to NKR ligands, which otherwise could possibly cause adverse activation or inhibition of T cells in this environment.