U
Ulrich Steinhoff
Researcher at University of Marburg
Publications - 92
Citations - 7257
Ulrich Steinhoff is an academic researcher from University of Marburg. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 34, co-authored 85 publications receiving 6339 citations. Previous affiliations of Ulrich Steinhoff include Max Planck Society & University of Zurich.
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Journal ArticleDOI
Functional role of type I and type II interferons in antiviral defense.
Ulrike Müller,Ulrich Steinhoff,Luiz F. L. Reis,Silvio Hemmi,Jovan Pavlovic,Rolf M. Zinkernagel,Michel Aguet +6 more
TL;DR: Comparison of mice lacking either type I or type II IFN receptors showed that, at least in response to some viruses, both IFN systems are essential for antiviral defense and are functionally nonredundant.
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TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity
Vicky Lampropoulou,Kai Hoehlig,Toralf Roch,Patricia Neves,Elisabeth Calderón Gómez,Claire H. Sweenie,Yi Hao,Antonio A. Freitas,Ulrich Steinhoff,Stephen M. Anderton,Simon Fillatreau +10 more
TL;DR: It is demonstrated that TLR-signaling in B cells suppresses inflammatory T cell responses, and stimulates recovery from EAE, indicating that B cells link recognition of microbial products via TLR to suppression of a T cell-mediated autoimmune disease.
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Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis
Hans-Willi Mittrücker,Ulrich Steinhoff,Anne Köhler,Marion Krause,Doris Lazar,Peggy Mex,Delia Miekley,Stefan H. E. Kaufmann +7 more
TL;DR: The data question the measurement of IFN-γ secretion by CD4+ T cells and emphasize the need for new biomarkers for evaluation of tuberculosis vaccine efficacies.
Journal ArticleDOI
Signaling via the MyD88 Adaptor Protein in B Cells Suppresses Protective Immunity during Salmonella typhimurium Infection
Patricia Neves,Vicky Lampropoulou,Elisabeth Calderon-Gomez,Toralf Roch,Ulrik Stervbo,Ping Shen,Anja A. Kühl,Christoph Loddenkemper,Matthias Haury,Sergei A. Nedospasov,Sergei A. Nedospasov,Stefan H. E. Kaufmann,Ulrich Steinhoff,Dinis Pedro Calado,Dinis Pedro Calado,Simon Fillatreau +15 more
TL;DR: It is demonstrated here that MyD88 expression in B cells inhibits resistance of mice to Salmonella typhimurium infection, and it is shown that interleukin-10 is an essential mediator of these inhibitory functions of B cells.
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Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments.
Rafael Di Marco Barros,Rafael Di Marco Barros,Rafael Di Marco Barros,Natalie A. Roberts,Robin J. Dart,Robin J. Dart,Pierre Vantourout,Anett Jandke,Oliver Nussbaumer,Livija Deban,Sara Cipolat,Rosie Hart,Maria Luisa Iannitto,Adam Laing,Bradley Spencer-Dene,Philip East,Deena L. Gibbons,Peter M. Irving,Pablo Pereira,Ulrich Steinhoff,Adrian Hayday,Adrian Hayday +21 more
TL;DR: A conserved mechanism emerges whereby epithelia use organ-specific BTNL/Btnl genes to shape local T cell compartments in murine enterocytes, evoking the developmental selection of TCRαβ+ repertoires.