Karina Biskup

TL;DR: This study is the first to compare glycan values with the established tumor marker CA125 and to give better results, indicating that the N-glycome could potentially be used as a biomarker in EOC-patients.

TL;DR: The results highlight EGFR-K521 expression as a key mechanism of cetuximab resistance to evaluate prospectively as a predictive biomarker in HNSCC patients and offer a preclinical rationale for the use of ADCC-optimized antibodies to treat tumors harboring this EGFR isoform.

TL;DR: GLYCOV was able to recognize stage I EOC whereas CA125 values were statistically significant only for stage II EOC patients and was more sensitive and specific in distinguishing early-stage EOC from BOD patients, which is of high relevance to clinicians as it is difficult for them to diagnose malignancy prior to operation.

TL;DR: In this paper , the authors show that Plasmodium falciparum (Pf)-infected red blood cells (RBCs) carry significantly higher sialylated complex N-glycans than those derived from healthy RBCs.

TL;DR: Very small superparamagnetic iron oxide nanoparticles in magnetic resonance imaging (MRI) present a potential contrast agent for contrast-enhanced MRI to detect intestinal inflammation in mice at an early stage and in a less invasive manner depending on hyaluronic acid content.