K
Karol P. Budohoski
Researcher at University of Cambridge
Publications - 110
Citations - 3582
Karol P. Budohoski is an academic researcher from University of Cambridge. The author has contributed to research in topics: Medicine & Cerebral blood flow. The author has an hindex of 26, co-authored 80 publications receiving 2718 citations. Previous affiliations of Karol P. Budohoski include Medical University of Warsaw & University of California, San Francisco.
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Journal ArticleDOI
Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury.
Marcel J. H. Aries,Marek Czosnyka,Karol P. Budohoski,Luzius A. Steiner,Andrea Lavinio,Angelos G. Kolias,Peter J. Hutchinson,Kenneth Martin Brady,David K. Menon,John D. Pickard,Peter Smielewski +10 more
TL;DR: Developing an automated methodology for the continuous updating of optimal cerebral perfusion pressure (CPPopt) for patients after severe traumatic head injury, using continuous monitoring of cerebrovascular pressure reactivity is sought.
Journal ArticleDOI
Critical thresholds for cerebrovascular reactivity after traumatic brain injury.
Enrico Sorrentino,Jennifer Diedler,Magdalena Kasprowicz,Karol P. Budohoski,Christina Haubrich,Peter Smielewski,Joanne G. Outtrim,Anne E. Manktelow,Peter J. Hutchinson,John D. Pickard,David K. Menon,Marek Czosnyka +11 more
TL;DR: The prognostic role of PRx is confirmed but with a lower threshold of 0.05 for favorable outcome than for survival (0.25) and the lower value in elderly and in females suggests increased vulnerability to intracranial hypertension in these groups.
Journal ArticleDOI
Transcranial Doppler Pulsatility Index: What it is and What it Isn’t
Nicolás de Riva,Nicolás de Riva,Karol P. Budohoski,Peter Smielewski,Magdalena Kasprowicz,Magdalena Kasprowicz,Christian Zweifel,Christian Zweifel,Luzius A. Steiner,Luzius A. Steiner,Matthias Reinhard,Matthias Reinhard,Neus Fàbregas,John D. Pickard,Marek Czosnyka,Marek Czosnyka +15 more
TL;DR: TCD pulsatility index can be easily and quickly assessed but is usually misinterpreted as a descriptor of CVR, which presents a complex relationship between PI and multiple haemodynamic variables.
Journal ArticleDOI
Impairment of Cerebral Autoregulation Predicts Delayed Cerebral Ischemia After Subarachnoid Hemorrhage A Prospective Observational Study
Karol P. Budohoski,Marek Czosnyka,Peter Smielewski,Magdalena Kasprowicz,Adel Helmy,Diederik Bulters,John D. Pickard,Peter J. Kirkpatrick +7 more
TL;DR: Disturbed autoregulation in the first 5 days after SAH significantly increases the risk of DCI, as detected using near-infrared spectroscopy and transcranial Doppler technologies.
Journal ArticleDOI
The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage
Karol P. Budohoski,Mathew R. Guilfoyle,Adel Helmy,Terhi Huuskonen,Marek Czosnyka,Ramez W. Kirollos,David K. Menon,John D. Pickard,Peter J. Kirkpatrick +8 more
TL;DR: The current knowledge about the mechanisms underlying the development of DCI is summarized and the known pharmacological treatment options with respect to the presumed mechanism of action and its role in DCI are described and categorised.