K
Kasha P. Singh
Researcher at Royal Melbourne Hospital
Publications - 40
Citations - 1046
Kasha P. Singh is an academic researcher from Royal Melbourne Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 25 publications receiving 837 citations. Previous affiliations of Kasha P. Singh include Chulalongkorn University & University of Melbourne.
Papers
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Journal ArticleDOI
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.
Laura J. Pallett,Upkar S. Gill,Alberto Quaglia,Linda V. Sinclair,M Jover-Cobos,Anna Schurich,Kasha P. Singh,Niclas Thomas,Abhishek Das,Antony Chen,Giuseppe Fusai,Antonio Bertoletti,Doreen A. Cantrell,Patrick T F Kennedy,Nathan Davies,Muzlifah Haniffa,Mala K. Maini +16 more
TL;DR: The capacity of expanded arginase-expressing gMDSCs to regulate liver immunopathology in HBV infection is demonstrated, providing in vitro and ex vivo evidence that gM DSCs potently inhibited T cells in a partially arkinase-dependent manner.
Journal ArticleDOI
HIV-hepatitis B virus coinfection: epidemiology, pathogenesis, and treatment.
Kasha P. Singh,Megan Crane,Jennifer Audsley,Anchalee Avihingsanon,Joe Sasadeusz,Sharon R Lewin +5 more
TL;DR: This paper reviews recent studies examining the natural history and pathogenesis of liver disease and seroconversion in HIV–HBV coinfection in the era of HBV-active antiretroviral therapy and the effects of HIV directly on liver disease.
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Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment
Sven O. Friedrich,Andrea Rachow,Andrea Rachow,Elmar Saathoff,Kasha P. Singh,Chacha Mangu,Rodney Dawson,Patrick P. J. Phillips,Amour Venter,Anna Bateson,Catharina Boehme,Norbert Heinrich,Robert D Hunt,Martin J. Boeree,Alimuddin Zumla,Timothy D. McHugh,Stephen H. Gillespie,Andreas H. Diacon,Michael Hoelscher +18 more
TL;DR: Compared with the combined binary smear and culture results as a reference standard, the Xpert MTB/RIF assay had high sensitivity, but poor specificity, and should not replace standard smear microscopy and culture.
Journal ArticleDOI
Expanding access to treatment for hepatitis C in resource-limited settings: Lessons from HIV/AIDS
Nathan Ford,Nathan Ford,Kasha P. Singh,Graham S Cooke,Graham S Cooke,Edward J Mills,Tido von Schoen-Angerer,Adeeba Kamarulzaman,Philipp du Cros +8 more
TL;DR: Key priorities for scaling up HCV treatment and care include reducing the cost of current and future treatment; simplifying the package of care; identifying opportunities to shift specific tasks to nonspecialists to overcome human resource constraints.
Journal ArticleDOI
Chronic hepatitis C treatment outcomes in low- and middle-income countries: a systematic review and meta-analysis
Nathan Ford,Catherine Kirby,Kasha P. Singh,Edward J Mills,Graham S Cooke,Adeeba Kamarulzaman,Philipp duCros +6 more
TL;DR: The outcomes of treatment for HCV infection in low- and middle- Income countries were similar to those reported in high-income countries.