J
Joe Sasadeusz
Researcher at Royal Melbourne Hospital
Publications - 130
Citations - 4605
Joe Sasadeusz is an academic researcher from Royal Melbourne Hospital. The author has contributed to research in topics: Hepatitis B & Hepatitis B virus. The author has an hindex of 34, co-authored 125 publications receiving 4192 citations. Previous affiliations of Joe Sasadeusz include National Health and Medical Research Council & Fairfield Hospital.
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Journal ArticleDOI
Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients.
Francesca J. Torriani,Maribel Rodriguez-Torres,Jürgen K. Rockstroh,Eduardo Lissen,Juan González-García,Adriano Lazzarin,Giampiero Carosi,Joe Sasadeusz,Christine Katlama,Julio S. G. Montaner,Sette H,Sharon Passe,Jean De Pamphilis,Frank Duff,Uschi Marion Schrenk,Douglas T. Dieterich +15 more
TL;DR: Among patients infected with both HIV and HCV, the combination of peginterferon alfa-2a plus ribavirin was significantly more effective than either interferonalfa- 2a plus Ribavirin or pegin terferonAlfa-3a monotherapy.
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HIV-hepatitis B virus coinfection: epidemiology, pathogenesis, and treatment.
Kasha P. Singh,Megan Crane,Jennifer Audsley,Anchalee Avihingsanon,Joe Sasadeusz,Sharon R Lewin +5 more
TL;DR: This paper reviews recent studies examining the natural history and pathogenesis of liver disease and seroconversion in HIV–HBV coinfection in the era of HBV-active antiretroviral therapy and the effects of HIV directly on liver disease.
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A randomized trial of combination hepatitis B therapy in HIV/HBV coinfected antiretroviral naïve individuals in Thailand
Gail V. Matthews,Anchalee Avihingsanon,Sharon R Lewin,Sharon R Lewin,Janaki Amin,Rungsun Rerknimitr,Panusit Petcharapirat,P. Marks,Joe Sasadeusz,David A. Cooper,Scott Bowden,Stephen Locarnini,Kiat Ruxrungtham,Gregory J. Dore +13 more
TL;DR: This study confirms current treatment guidelines that recommend a TDF‐based regimen as the treatment of choice for HIV/HBV coinfection, but does not demonstrate any advantage of HBV combination therapy in this short‐term setting.
Journal ArticleDOI
Homopolymer mutational hot spots mediate herpes simplex virus resistance to acyclovir.
Joe Sasadeusz,Frank Tufaro,S. Safrin,K Schubert,M M Hubinette,Peter K. Cheung,Stephen L. Sacks +6 more
TL;DR: It is demonstrated that the majority of ACVr clinical isolates contain frameshift mutations within two long homopolymer nucleotide stretches which function as hot spots within the HSV tk gene and produce nonfunctional, truncated TK proteins.
Journal ArticleDOI
Varicella-zoster infection after allogeneic bone marrow transplantation: incidence, risk factors and prevention with low-dose aciclovir and ganciclovir
TL;DR: It is concluded that 3–6 months of low-dose aciclovir and ganciclovIR are effective at delaying the onset of VZV after allogeneic BMT, but may not affect the overall incidence of infection.