K
Kathryn E. Stockbauer
Researcher at Baylor College of Medicine
Publications - 14
Citations - 2908
Kathryn E. Stockbauer is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Gene & Streptococcus pyogenes. The author has an hindex of 12, co-authored 14 publications receiving 2812 citations. Previous affiliations of Kathryn E. Stockbauer include Houston Methodist Hospital.
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Journal ArticleDOI
Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination
Srinand Sreevatsan,Xi Pan,Kathryn E. Stockbauer,Nancy D. Connell,Barry N. Kreiswirth,Thomas S. Whittam,James M. Musser +6 more
TL;DR: Sequence analysis of two megabases in 26 structural genes or loci in strains recovered globally discovered a striking reduction of silent nucleotide substitutions compared with other human bacterial pathogens, indicating that M. tuberculosis is evolutionarily young and has recently spread globally.
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The emb operon, a gene cluster of mycobacterium tuberculosis involved in resistance to ethambutol
Amalio Telenti,Wolfgang J. Philipp,Srinand Sreevatsan,C Bernasconi,Kathryn E. Stockbauer,Brigitte Wieles,James M. Musser,William R. Jacobs +7 more
TL;DR: This work used resistance to EMB as a tool to identify genes participating in the biosynthesis of the mycobacterial cell wall and led to the identification of the embCAB gene cluster, recently proposed to encode for myc Cobacterium tuberculosis arabinosyl transferases.
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Origin and interstate spread of a New York City multidrug-resistant Mycobacterium tuberculosis clone family
Pablo Bifani,Bonnie B. Plikaytis,Vivek Kapur,Vivek Kapur,Kathryn E. Stockbauer,Xi Pan,Michael L. Lutfey,Soraya L. Moghazeh,William Eisner,Thomas M. Daniel,Mark H. Kaplan,Jack T. Crawford,James M. Musser,Barry N. Kreiswirth +13 more
TL;DR: The results document the molecular origin and spread of progeny of a closely related family of multidrug-resistant M tuberculosis strains that have recently shared a common ancestor and undergone clonal expansion.
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Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations.
Srinand Sreevatsan,Kathryn E. Stockbauer,Xi Pan,Barry N. Kreiswirth,Soraya L. Moghazeh,William R. Jacobs,Amalio Telenti,James M. Musser,James M. Musser +8 more
TL;DR: The data are consistent with the idea that amino acid substitutions in EmbB alter the drug-protein interaction and thereby cause EMB resistance.
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Characterization of rpsL and rrs mutations in streptomycin-resistant Mycobacterium tuberculosis isolates from diverse geographic localities.
Srinand Sreevatsan,Xi Pan,Kathryn E. Stockbauer,Diana L. Williams,Barry N. Kreiswirth,James M. Musser,James M. Musser +6 more
TL;DR: Two genes (rpsL and rrs) with mutations associated with streptomycin resistance in Mycobacterium tuberculosis were characterized in 78 strePTomycin-resistant and 61 streptomecin-susceptible isolates recovered from patients living in the United States, South America, Europe, Africa, and Asia.