K
Kathryn M Rowan
Researcher at University of London
Publications - 9
Citations - 4322
Kathryn M Rowan is an academic researcher from University of London. The author has contributed to research in topics: Early goal-directed therapy & Intensive care. The author has an hindex of 7, co-authored 9 publications receiving 2467 citations.
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Journal ArticleDOI
Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study
Kristina E. Rudd,Sarah Charlotte Johnson,Kareha M Agesa,Katya Anne Shackelford,Derrick Tsoi,Daniel Kievlan,Danny V. Colombara,Kevin S Ikuta,Kevin S Ikuta,Niranjan Kissoon,Simon Finfer,Carolin Fleischmann-Struzek,Flávia Ribeiro Machado,Konrad Reinhart,Kathryn M Rowan,Christopher W. Seymour,R. Scott Watson,R. Scott Watson,T. Eoin West,Fatima Marinho,Simon I. Hay,Simon I. Hay,Rafael Lozano,Rafael Lozano,Alan D. Lopez,Alan D. Lopez,Derek C. Angus,Christopher J L Murray,Christopher J L Murray,Mohsen Naghavi,Mohsen Naghavi +30 more
TL;DR: Despite declining age-standardised incidence and mortality, sepsis remains a major cause of health loss worldwide and has an especially high health-related burden in sub-Saharan Africa.
Journal ArticleDOI
Trial of Early, Goal-Directed Resuscitation for Septic Shock
Paul R Mouncey,Tiffany M. Osborn,G. Sarah Power,David A Harrison,M Zia Sadique,Richard Grieve,Rahi Jahan,Sheila Harvey,Derek Bell,Julian Bion,Timothy J Coats,Mervyn Singer,J Duncan Young,Kathryn M Rowan,Abstr Act +14 more
TL;DR: In patients with septic shock who were identified early and received intravenous antibiotics and adequate fluid resuscitation, hemodynamic management according to a strict EGDT protocol did not lead to an improvement in outcome.
Journal ArticleDOI
Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
Prism Investigators,Kathryn M Rowan,Derek C. Angus,Michael Bailey,Amber E. Barnato,Rinaldo Bellomo,Ruth R Canter,Timothy J Coats,Anthony Delaney,Elizabeth Gimbel,Richard Grieve,David A Harrison,Alisa Higgins,Belinda Howe,David T. Huang,John A. Kellum,Paul R Mouncey,Edvin Music,Sandra L. Peake,Sandra L. Peake,Francis Pike,Michael C. Reade,M Zia Sadique,Mervyn Singer,Donald M. Yealy +24 more
TL;DR: In this meta‐analysis of individual patient data, EGDT did not result in better outcomes than usual care and was associated with higher hospitalization costs across a broad range of patient and hospital characteristics.
Journal ArticleDOI
Hospital mortality associated with day and time of admission to intensive care units
TL;DR: After appropriate adjustment for case mix, day of the week and time of day of admission of patients to ICU were not associated with significant differences in hospital mortality.
Journal ArticleDOI
Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock
Paul R Mouncey,Tiffany M. Osborn,G. Sarah Power,David A Harrison,M Zia Sadique,Richard Grieve,Rahi Jahan,Jermaine C K Tan,Sheila Harvey,Derek Bell,Derek Bell,Julian Bion,Timothy J Coats,Mervyn Singer,J Duncan Young,Kathryn M Rowan +15 more
TL;DR: There was no significant difference in all-cause mortality at 90 days for EGDT compared with usual resuscitation among adults identified with early septic shock presenting to EDs in England.