Katja Schwartz

TL;DR: The authors' within-lane normalization procedures, followed by between-lanenormalization, reduce GC-content bias and lead to more accurate estimates of expression fold-changes and tests of differential expression.

TL;DR: This work observes a highly structured pattern of DNA fragment lengths and positions around nucleosomes in Saccharomyces cerevisiae, and uses this distinctive two-dimensional nucleosomal "fingerprint" as the basis for a new nucleosome-positioning algorithm called NucleoATAC, which can identify the rotational and translational positions ofucleosomes with up to base-pair resolution.

TL;DR: The sequence of BIM1 shows substantial similarity to sequences from organisms across the evolutionary spectrum and a systematic study of 51 tub1 alleles suggests a correlation between specific failure to interact with Bim1p in the two-hybrid assay and synthetic lethality with the bim1Delta allele.

TL;DR: It is demonstrated that natural S. cerevisiae yeasts are capable of utilizing xylose as the sole carbon source, the genetic basis for this trait as well as the endogenous xylOSE utilization pathway are characterized, and the feasibility of BSA is demonstrated using high-throughput sequencing.

TL;DR: Evidence of gene flow between previously known and newly identified genetic clusters is found, supporting the occurrence of parasexuality in nature and thus C. albicans takes advantage of both clonality and gene flow to diversify.