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Showing papers by "Kazunori Yamada published in 2020"

Journal Article•DOI•
Impaired expression of innate immunity-related genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD.

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Takuji Nakamura1, Tomomi Satoh-Nakamura1, Akio Nakajima1, Takafumi Kawanami1, Tomoyuki Sakai1, Yoshimasa Fujita1, Haruka Iwao1, Miyuki Miki1, Yasufumi Masaki1, Toshiro Okazaki1, Yasuhito Ishigaki1, Mitsuhiro Kawano2, Kazunori Yamada2, Shoko Matsui3, Takako Saeki, Terumi Kamisawa, Motohisa Yamamoto4, Hideaki Hamano5, Tomoki Origuchi6, Shintaro Hirata7, Yoshiya Tanaka, Hiroto Tsuboi8, Takayuki Sumida8, Kazuichi Okazaki9, Masao Tanaka1, Masao Tanaka10, Tsutomu Chiba10, Tsuneyo Mimori10, Hisanori Umehara1 •
Kanazawa Medical University1, Kanazawa University2, University of Toyama3, Sapporo Medical University4, Shinshu University5, RMIT University6, Hiroshima University7, University of Tsukuba8, Kansai Medical University9, Kyoto University10
03 May 2020-Modern Rheumatology
TL;DR: Results indicate that reduction in expression of innate immunity-related genes may participate in the pathogenesis of IgG4-RD that steroid treatment may rectify impaired innate immunity as well as acquired immunity.
Abstract: Background: IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and tissue infiltration by IgG4-positive plasma cells. The pathogenesis of this disease is not clear. Transcriptom...

6 citations