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Kazuya Yamanaka

Researcher at Kansai University

Publications -  31
Citations -  1395

Kazuya Yamanaka is an academic researcher from Kansai University. The author has contributed to research in topics: Amino acid & Nonribosomal peptide. The author has an hindex of 16, co-authored 27 publications receiving 1138 citations. Previous affiliations of Kazuya Yamanaka include University of California, San Diego.

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Journal ArticleDOI

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A

Kazuya Yamanaka, +8 more
- 04 Feb 2014 - 
TL;DR: A TAR-based genetic platform that allows us to directly clone, refactor, and heterologously express a silent biosynthetic pathway to yield a new antibiotic is reported.
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Biosynthesis of polybrominated aromatic organic compounds by marine bacteria

Vinayak Agarwal, +7 more
- 01 Aug 2014 - 
TL;DR: In this article, the authors report marine bacteria as producers of polybrominated diphenyl ethers (PBDEs) and establish a genetic and molecular foundation for their production that unifies paradigms for the elaboration of bromophenols and bromopyrroles abundant in marine biota.
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ε-Poly- L -lysine dispersity is controlled by a highly unusual nonribosomal peptide synthetase

Kazuya Yamanaka, +5 more
- 01 Dec 2008 - 
TL;DR: Pls is a new single-module NRPS having an amino acid ligase-like catalytic activity for peptide bond formation and is found to be a membrane protein with adenylation and thiolation domains characteristic of the nonribosomal peptide synthetases (NRPSs).
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Mechanism of ε-Poly-l-Lysine Production and Accumulation Revealed by Identification and Analysis of an ε-Poly-l-Lysine-Degrading Enzyme

Kazuya Yamanaka, +5 more
- 01 Sep 2010 - 
TL;DR: The identification of the gene encoding the ε-PL-degrading enzyme (PldII) is reported, which plays a central role in δ-PL degradation in this strain of Streptomyces albulus NBRC14147, and it was found that acidic pH conditions during η-PL fermentation are necessary for the accumulation of intracellular ATP.
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Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis

Yongxin Li, +8 more
- 24 Mar 2015 - 
TL;DR: This work represents the first direct cloning based heterologous expression of natural products in the model organism B. subtilis and paves the way to the development of future genome mining efforts in this genus.