K
Kees Besse
Researcher at Radboud University Nijmegen Medical Centre
Publications - 13
Citations - 607
Kees Besse is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Cancer pain & Pain assessment. The author has an hindex of 8, co-authored 13 publications receiving 524 citations. Previous affiliations of Kees Besse include Radboud University Nijmegen.
Papers
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Journal ArticleDOI
Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial
Sharon Ooms,Sebastiaan Overeem,Kees Besse,Marcel G. M. Olde Rikkert,Marcel M. Verbeek,Jurgen A.H.R. Claassen +5 more
TL;DR: It is hypothesized that chronic sleep deprivation increases cerebral Aβ42 levels, which elevates the risk of Alzheimer disease, and interferes with a physiological morning decrease in A β42.
Journal ArticleDOI
Opioid rotation in the management of chronic pain: where is the evidence?
TL;DR: In this article, the authors proposed to switch from one opioid to another while maintaining an acceptable side effect profile or even improving the side effects, based on the clinical response of the patient.
Journal ArticleDOI
23. Pain in patients with cancer.
Kris Vissers,Kees Besse,M. F. M. Wagemans,Wouter W.A. Zuurmond,Maurice J.M.M. Giezeman,Arno Lataster,Nagy Mekhail,Allen W. Burton,Maarten van Kleef,Frank J P M Huygen +9 more
TL;DR: Earlier application of interventional pain management techniques can be recommended even before considering the use of strong opioids in cancer patients, which provides better pain control, allows the reduction of analgesics and hence improves quality of life.
Journal ArticleDOI
Hourly variability of cerebrospinal fluid biomarkers in Alzheimer's disease subjects and healthy older volunteers.
Diane Slats,Jurgen A.H.R. Claassen,Petra E. Spies,George F. Borm,Kees Besse,William van Aalst,Jack Tseng,Magnus Sjögren,Marcel G.M. Olde Rikkert,Marcel M. Verbeek +9 more
TL;DR: Continuous sampling of CSF proved to be a useful and robust method, which may also be used to investigate AD pathogenesis and to evaluate pharmacotherapeutic interventions, and suggest that CSF biomarker variability is relatively low in healthy older controls and AD patients.
Book ChapterDOI
Pain in patients with cancer
K.C.P. Vissers,Kees Besse,M. F. M. Wagemans,Wouter W.A. Zuurmond,Maurice J.M.M. Giezeman,Arno Lataster,Nagy Mekhail,Allen W. Burton,M. van Kleef,F. Huygen +9 more
TL;DR: Earlier application of interventional pain management techniques can be recommended even before considering the use of strong opioids in cancer patients, while maintaining or even improving the pain relief and reducing the side effects.