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Jurgen A.H.R. Claassen

Researcher at Radboud University Nijmegen

Publications -  199
Citations -  7289

Jurgen A.H.R. Claassen is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Cerebral blood flow & Dementia. The author has an hindex of 40, co-authored 176 publications receiving 5221 citations. Previous affiliations of Jurgen A.H.R. Claassen include University of Texas Southwestern Medical Center & Presbyterian Hospital of Dallas.

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Cerebral Autoregulation: An Overview of Current Concepts and Methodology with Special Focus on the Elderly:

Arenda H.E.A. van Beek, +3 more
- 19 Mar 2008 - 
TL;DR: Of the various dynamic assessments of CA, a single sit-to-stand procedure is a feasible and physiologic method in the elderly, and the collection of spontaneous beat- to-beat changes in BP and CBF allows estimation of CA using the technique of transfer function analysis.
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New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, +401 more
- 01 Apr 2022 - 
TL;DR: This paper performed a two-stage genome-wide association study with 111,326 clinically diagnosed/proxy AD cases and 677,663 controls and found 75 risk loci, of which 42 were new at the time of analysis.
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Transfer function analysis of dynamic cerebral autoregulation: A white paper from the International Cerebral Autoregulation Research Network.

Jurgen A.H.R. Claassen, +3 more
- 18 Jan 2016 - 
TL;DR: The purpose of the present white paper is to improve standardisation of parameters and settings adopted for application of transfer function analysis in studies of dynamic cerebral autoregulation.
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Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels.

Yo-El Ju, +10 more
- 01 Aug 2017 - 
TL;DR: Slow wave activity disruption increases amyloid-β levels acutely, and poorer sleep quality over several days increases tau, which suggests they are likely driven by changes in neuronal activity during disrupted sleep.
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Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial

Sharon Ooms, +5 more
- 01 Aug 2014 - 
TL;DR: It is hypothesized that chronic sleep deprivation increases cerebral Aβ42 levels, which elevates the risk of Alzheimer disease, and interferes with a physiological morning decrease in A β42.