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Kelvin Y. C. Lee
Researcher at Singapore National Eye Center
Publications - 27
Citations - 1040
Kelvin Y. C. Lee is an academic researcher from Singapore National Eye Center. The author has contributed to research in topics: Glaucoma & Effusion. The author has an hindex of 16, co-authored 27 publications receiving 959 citations. Previous affiliations of Kelvin Y. C. Lee include University of Tokyo.
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Journal ArticleDOI
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma
Eranga N. Vithana,Eranga N. Vithana,Chiea Chuen Khor,Chiea Chuen Khor,Chiea Chuen Khor,Chunyan Qiao,Monisha E. Nongpiur,Monisha E. Nongpiur,Ronnie George,Li Jia Chen,Do Tan,Do Tan,Khaled K. Abu-Amero,Khaled K. Abu-Amero,Chor Kai Huang,Sancy Low,Liza-Sharmini Ahmad Tajudin,Shamira A. Perera,Ching-Yu Cheng,Ching-Yu Cheng,Liang Xu,Hongyan Jia,Ching-Lin Ho,Kar Seng Sim,Ren-Yi Wu,Ren-Yi Wu,Clement C Y Tham,Paul T K Chew,Daniel H. Su,Francis T.S. Oen,Sripriya Sarangapani,Nagaswamy Soumittra,Essam A. Osman,Hon-Tym Wong,Guangxian Tang,Sujie Fan,Hailin Meng,Dao Tl Huong,Hua Wang,Bo Feng,Mani Baskaran,Balekudaru Shantha,Vedam L. Ramprasad,Govindasamy Kumaramanickavel,Sudha K. Iyengar,Alicia C. How,Kelvin Y. C. Lee,Theru A. Sivakumaran,Victor H. K. Yong,Serena Ml Ting,Yang Li,Ya Xing Wang,Wan Ting Tay,Xueling Sim,Raghavan Lavanya,Belinda K. Cornes,Yingfeng Zheng,Yingfeng Zheng,Tina T. Wong,Seng-Chee Loon,Vernon Yong,Naushin Waseem,Azhany Yaakub,Kee Seng Chia,R. Rand Allingham,Michael A. Hauser,Dennis S.C. Lam,Martin L. Hibberd,Martin L. Hibberd,Shomi S. Bhattacharya,Mingzhi Zhang,Yik Ying Teo,Yik Ying Teo,Donald T. Tan,Donald T. Tan,Jost B. Jonas,E-Shyong Tai,Seang-Mei Saw,Seang-Mei Saw,Nhu Hon Do,Saleh A. Al-Obeidan,Jianjun Liu,Jianjun Liu,Nguyen Tran,Cameron P. Simmons,Jin-Xin Bei,Yi Xin Zeng,Paul J. Foster,Lingam Vijaya,Tien Yin Wong,Chi Pui Pang,Ningli Wang,Tin Aung,Tin Aung +93 more
TL;DR: A genome-wide association study including 1,854 PACG cases and 9,608 controls across 5 sample collections in Asia suggests possible mechanisms explaining the pathogenesis of PACG.
Journal ArticleDOI
Association analysis of CFH, C2, BF, and HTRA1 gene polymorphisms in Chinese patients with polypoidal choroidal vasculopathy.
Kelvin Y. C. Lee,Eranga N. Vithana,Ranjana Mathur,Victor S.H Yong,Ian Yeo,Anbupalam Thalamuthu,Mun-Wai Lee,Adrian Koh,Lim Mc,Alicia C. How,Doric Wong,Tin Aung +11 more
TL;DR: The SNPs rs3753394 and rs800292 of CFH and rs11200638 of HTRA1 are significantly associated with the risk of PCV in Chinese patients.
Journal ArticleDOI
Association of LOXL1 gene polymorphisms with pseudoexfoliation in the Japanese.
Mineo Ozaki,Kelvin Y. C. Lee,Eranga N. Vithana,Victor H. K. Yong,Anbupalam Thalamuthu,Takanori Mizoguchi,Anandalakshmi Venkatraman,Tin Aung +7 more
TL;DR: Polymorphisms in the LOXL1 gene confer risk to XFS/XFG in the Japanese, but there are different risk-associated alleles and haplotypes in theJapanese.
Journal ArticleDOI
Plateau Iris in Asian Subjects With Primary Angle Closure Glaucoma
Rajesh S. Kumar,Visanee Tantisevi,Melissa H. Y. Wong,Kobkuea Laohapojanart,Orathai Chansanti,Desmond Quek,Victor Koh,Lakshmana S. MohanRam,Kelvin Y. C. Lee,Prin Rojanapongpun,Tin Aung +10 more
TL;DR: About 30% of PACG eyes with a patent laser peripheral iridotomy were found to have plateau iris on UBM, highlighting the importance of non-pupil block mechanisms in Asian individuals.
Journal ArticleDOI
Characterization of Bietti crystalline dystrophy patients with CYP4V2 mutations.
Kelvin Y. C. Lee,Adrian Koh,Tin Aung,Victor H. K. Yong,Kit Yeung,Chong Lye Ang,Eranga N. Vithana +6 more
TL;DR: This study identified novel mutations in the CYP4V2 gene as a cause of BCD and identified a high carrier frequency for the 15-bp deletion in exon 7, which may exist in the Singapore population.