K
Khaled K. Abu-Amero
Researcher at King Saud University
Publications - 209
Citations - 5781
Khaled K. Abu-Amero is an academic researcher from King Saud University. The author has contributed to research in topics: Population & Mitochondrial DNA. The author has an hindex of 40, co-authored 209 publications receiving 5152 citations. Previous affiliations of Khaled K. Abu-Amero include University of Illinois at Chicago & King Abdulaziz University.
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Journal ArticleDOI
Mitochondrial abnormalities in patients with primary open-angle glaucoma.
TL;DR: A spectrum of mitochondrial abnormalities in patients with POAG is revealed, implicating oxidative stress and implying that mitochondria dysfunction may be a risk factor for POAG.
Journal ArticleDOI
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma
Eranga N. Vithana,Eranga N. Vithana,Chiea Chuen Khor,Chiea Chuen Khor,Chiea Chuen Khor,Chunyan Qiao,Monisha E. Nongpiur,Monisha E. Nongpiur,Ronnie George,Li Jia Chen,Do Tan,Do Tan,Khaled K. Abu-Amero,Khaled K. Abu-Amero,Chor Kai Huang,Sancy Low,Liza-Sharmini Ahmad Tajudin,Shamira A. Perera,Ching-Yu Cheng,Ching-Yu Cheng,Liang Xu,Hongyan Jia,Ching-Lin Ho,Kar Seng Sim,Ren-Yi Wu,Ren-Yi Wu,Clement C Y Tham,Paul T K Chew,Daniel H. Su,Francis T.S. Oen,Sripriya Sarangapani,Nagaswamy Soumittra,Essam A. Osman,Hon-Tym Wong,Guangxian Tang,Sujie Fan,Hailin Meng,Dao Tl Huong,Hua Wang,Bo Feng,Mani Baskaran,Balekudaru Shantha,Vedam L. Ramprasad,Govindasamy Kumaramanickavel,Sudha K. Iyengar,Alicia C. How,Kelvin Y. C. Lee,Theru A. Sivakumaran,Victor H. K. Yong,Serena Ml Ting,Yang Li,Ya Xing Wang,Wan Ting Tay,Xueling Sim,Raghavan Lavanya,Belinda K. Cornes,Yingfeng Zheng,Yingfeng Zheng,Tina T. Wong,Seng-Chee Loon,Vernon Yong,Naushin Waseem,Azhany Yaakub,Kee Seng Chia,R. Rand Allingham,Michael A. Hauser,Dennis S.C. Lam,Martin L. Hibberd,Martin L. Hibberd,Shomi S. Bhattacharya,Mingzhi Zhang,Yik Ying Teo,Yik Ying Teo,Donald T. Tan,Donald T. Tan,Jost B. Jonas,E-Shyong Tai,Seang-Mei Saw,Seang-Mei Saw,Nhu Hon Do,Saleh A. Al-Obeidan,Jianjun Liu,Jianjun Liu,Nguyen Tran,Cameron P. Simmons,Jin-Xin Bei,Yi Xin Zeng,Paul J. Foster,Lingam Vijaya,Tien Yin Wong,Chi Pui Pang,Ningli Wang,Tin Aung,Tin Aung +93 more
TL;DR: A genome-wide association study including 1,854 PACG cases and 9,608 controls across 5 sample collections in Asia suggests possible mechanisms explaining the pathogenesis of PACG.
Journal ArticleDOI
Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease.
Canny Sugiana,David J. Pagliarini,David J. Pagliarini,Matthew McKenzie,Denise M. Kirby,Renato Salemi,Khaled K. Abu-Amero,Hans Henrik M. Dahl,Wendy M. Hutchison,Katherine A. Vascotto,Stacey M. Smith,Robert F. Newbold,John Christodoulou,Sarah E. Calvo,Sarah E. Calvo,Vamsi K. Mootha,Vamsi K. Mootha,Michael T. Ryan,David R. Thorburn,David R. Thorburn +19 more
TL;DR: It is shown that C20orf7 is peripherally associated with the matrix face of the mitochondrial inner membrane and that silencing its expression with RNAi decreases complex I activity, and that mutations in C 20orf7 cause mitochondrial disease.
Journal ArticleDOI
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma
Chiea Chuen Khor,Chiea Chuen Khor,Tan Do,Hongyan Jia,Masakazu Nakano,Ronnie George,Khaled K. Abu-Amero,Khaled K. Abu-Amero,Roopam Duvesh,Li Jia Chen,Zheng Li,Monisha E. Nongpiur,Shamira A. Perera,Chunyan Qiao,Hon-Tym Wong,Hiroshi Sakai,M B Melo,Mei Chin Lee,Anita S. Chan,Yaakub Azhany,Thi Lam Huong Dao,Yoko Ikeda,Rodolfo A. Perez-Grossmann,Tomasz Zarnowski,Alexander C Day,Alexander C Day,Alexander C Day,Jost B. Jonas,Pancy O. S. Tam,Tuan Anh Tran,Humaira Ayub,Farah Akhtar,Shazia Micheal,Paul T K Chew,Leyla Al-Jasim,Tanuj Dada,Tam Thi Luu,Mona S Awadalla,Naris Kitnarong,Boonsong Wanichwecharungruang,Yee Yee Aung,Jelinar Mohamed-Noor,Saravanan Vijayan,Sripriya Sarangapani,Rahat Husain,Rahat Husain,Aliza Jap,Aliza Jap,Mani Baskaran,David Goh,Daniel H. Su,Huaizhou Wang,Vernon Yong,Leonard W. Yip,Tuyet Bach Trinh,Manchima Makornwattana,Thanh Thu Nguyen,Edgar U Leuenberger,Ki Ho Park,Widya Artini Wiyogo,Rajesh S. Kumar,Celso Tello,Yasuo Kurimoto,Suman S Thapa,Kessara Pathanapitoon,John F Salmon,Yong Ho Sohn,Antonio Maria Fea,Mineo Ozaki,Jimmy S. M. Lai,Visanee Tantisevi,Chaw Chaw Khaing,Takanori Mizoguchi,Satoko Nakano,Chan-Yun Kim,Guangxian Tang,Sujie Fan,Ren-Yi Wu,Hailin Meng,Thi Nguyen,Tien Dat Tran,Morio Ueno,Jose Maria Martinez,Norlina Ramli,Yin Mon Aung,Rigo Daniel Reyes,Stephen A Vernon,Seng Kheong Fang,Z. Xie,Xiao Yin Chen,Jia Nee Foo,Kar Seng Sim,Tina T. Wong,Desmond Quek,Rengaraj Venkatesh,Srinivasan Kavitha,Subbiah. R. Krishnadas,Nagaswamy Soumittra,Balekudaru Shantha,Boon-Ang Lim,Jeanne J. Ogle,José Paulo Cabral de Vasconcellos,Vital Paulino Costa,Ricardo Y. Abe,Bruno Batista de Souza,Chelvin C A Sng,Maria Cecilia Aquino,Ewa Kosior-Jarecka,Guillermo Barreto Fong,Vania Castro Tamanaja,Ricardo Fujita,Yuzhen Jiang,Yuzhen Jiang,Yuzhen Jiang,Naushin Waseem,Naushin Waseem,Sancy Low,Sancy Low,Sancy Low,Huan Nguyen Pham,Sami Al-Shahwan,E. Randy Craven,Muhammad Imran Khan,Rrima Dada,Kuldeep Mohanty,Muneeb A. Faiq,Alex W. Hewitt,Alex W. Hewitt,Kathryn P. Burdon,Kathryn P. Burdon,Eng Hui Gan,Anuwat Prutthipongsit,Thipnapa Patthanathamrongkasem,Mary Ann T Catacutan,Irene R Felarca,Chona S Liao,Emma Rusmayani,Vira Wardhana Istiantoro,Giulia Consolandi,Giulia Pignata,Carlo Lavia,Prin Rojanapongpun,Lerprat Mangkornkanokpong,Sunee Chansangpetch,Jonathan C.H. Chan,Bonnie Nga Kwan Choy,Jennifer W. H. Shum,Hlaing May Than,Khin Thida Oo,Aye Thi Han,Victor H. K. Yong,Xiao-Yu Ng,Shuang Ru Goh,Yaan Fun Chong,Martin L. Hibberd,Mark Seielstad,Eileen Png,Sarah J. Dunstan,Sarah J. Dunstan,Nguyen Van Vinh Chau,Jin-Xin Bei,Yi Xin Zeng,Yi Xin Zeng,Abhilasha Karkey,Buddha Basnyat,Francesca Pasutto,Daniela Paoli,Paolo Frezzotti,Jie Jin Wang,Paul Mitchell,John H. Fingert,John H. Fingert,R. Rand Allingham,R. Rand Allingham,Michael A. Hauser,Michael A. Hauser,Soon Thye Lim,Soo Hong Chew,Richard P. Ebstein,Anavaj Sakuntabhai,Anavaj Sakuntabhai,Kyu Hyung Park,Jeeyun Ahn,Greet J. Boland,Harm Snippe,Richard Stead,Raquel Quino,Su Nyunt Zaw,Urszula Lukasik,Rohit Shetty,Mimiwati Zahari,Hyoung Won Bae,Nay Lin Oo,Toshiaki Kubota,Anita Manassakorn,Wing Lau Ho,Laura Dallorto,Young Hoon Hwang,Christine A. Kiire,Masako Kuroda,Zeiras Eka Djamal,Jovell Ian M Peregrino,Arkasubhra Ghosh,Jin Wook Jeoung,Tung S Hoan,Nuttamon Srisamran,Thayanithi Sandragasu,Saw Htoo Set,Vi Huyen Doan,Shomi S. Bhattacharya,Ching-Lin Ho,Donald T.H. Tan,Ramanjit Sihota,Seng-Chee Loon,Kazuhiko Mori,Shigeru Kinoshita,Anneke I. den Hollander,Raheel Qamar,Raheel Qamar,Ya Xing Wang,Yik Y. Teo,E-Shyong Tai,Curt Hartleben-Matkin,David Lozano-Giral,Seang-Mei Saw,Ching-Yu Cheng,Juan Carlos Zenteno,Chi Pui Pang,Huong T T Bui,Owen Hee,Jamie E Craig,Deepak P. Edward,Michiko Yonahara,Jamil Miguel Neto,Maria Luisa Guevara-Fujita,Liang Xu,Robert Ritch,Ahmad Tajudin Liza-Sharmini,Tien Yin Wong,Saleh A. Al-Obeidan,Nhu Hon Do,Periasamy Sundaresan,Clement C Y Tham,Paul J. Foster,Paul J. Foster,Paul J. Foster,Lingam Vijaya,Lingam Vijaya,Kei Tashiro,Eranga N. Vithana,Ningli Wang,Tin Aung +251 more
TL;DR: It is confirmed that significant association at three previously described loci (P < 5 × 10−8 for each sentinel SNP at PLEKHA7, COL11A1, and PCMTD1–ST18), providing new insights into the biology of PACG, is confirmed.
Journal ArticleDOI
Successful pregnancies after application of array-comparative genomic hybridization in PGS-aneuploidy screening.
TL;DR: This report is the first to show a pregnancy after preimplantation genetic screening using the aCGH technology, and will open the door for enrollment of more patients.