R
R. Rand Allingham
Researcher at Duke University
Publications - 253
Citations - 11946
R. Rand Allingham is an academic researcher from Duke University. The author has contributed to research in topics: Glaucoma & Population. The author has an hindex of 61, co-authored 253 publications receiving 10573 citations. Previous affiliations of R. Rand Allingham include Alcon & Massachusetts Eye and Ear Infirmary.
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Journal ArticleDOI
Cerebrospinal fluid pressure is decreased in primary open-angle glaucoma.
TL;DR: Cerebrospinal fluid pressure is significantly lower in POAG patients compared with that in nonglaucomatous controls, and the notion that CSF pressure may play an important contributory role in the pathogenesis of POAG is supported.
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Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case-control study.
TL;DR: Intacranial pressure may play an important role in the development of POAG and NTG and in preventing the progression of OHT toPOAG and in protecting against the pathogenesis of glaucoma.
Journal ArticleDOI
Central Corneal Thickness in Normal, Glaucomatous, and Ocular Hypertensive Eyes
TL;DR: The mean CCT is increased in eyes with ocular hypertension when compared with normal or glaucomatous eyes, which confirms the findings of other investigators.
Journal ArticleDOI
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
Yi Lu,Veronique Vitart,Kathryn P. Burdon,Chiea Chuen Khor,Yelena Bykhovskaya,Alireza Mirshahi,Alex W. Hewitt,Alex W. Hewitt,Demelza Koehn,Pirro G. Hysi,Wishal D. Ramdas,Tanja Zeller,Eranga N. Vithana,Belinda K. Cornes,Wan Ting Tay,E. Shyong Tai,Ching-Yu Cheng,Jianjun Liu,Jianjun Liu,Jia Nee Foo,Seang-Mei Saw,Gudmar Thorleifsson,Kari Stefansson,Kari Stefansson,David P. Dimasi,Richard A. Mills,Jenny Mountain,Wei Ang,René Hoehn,Virginie J. M. Verhoeven,Franz H. Grus,Roger C. W. Wolfs,Raphaële Castagné,Karl J. Lackner,Henriët Springelkamp,Jian Yang,Fridbert Jonasson,Dexter Y L Leung,Li J. Chen,Clement C Y Tham,Igor Rudan,Igor Rudan,Zoran Vatavuk,Caroline Hayward,Jane Gibson,Angela J. Cree,Alex MacLeod,Sarah Ennis,Ozren Polasek,Harry Campbell,James F. Wilson,Ananth C. Viswanathan,Brian W Fleck,Xiaohui Li,David S. Siscovick,Kent D. Taylor,Jerome I. Rotter,Seyhan Yazar,Megan Ulmer,Jun Li,Brian L. Yaspan,Ayse Bilge Ozel,Julia E. Richards,Sayoko E. Moroi,Jonathan L. Haines,Jae H. Kang,Louis R. Pasquale,Louis R. Pasquale,R. Rand Allingham,Allison E. Ashley-Koch,Paul Mitchell,Jie Jin Wang,Alan F. Wright,Craig E. Pennell,Tim D. Spector,Terri L. Young,Terri L. Young,Caroline C W Klaver,Nicholas G. Martin,Grant W. Montgomery,Michael G. Anderson,Tin Aung,Colin E. Willoughby,Janey L. Wiggs,Chi P. Pang,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Andrew J. Lotery,Christopher J Hammond,Cornelia M. van Duijn,Michael A. Hauser,Yaron S. Rabinowitz,Norbert Pfeiffer,David A. Mackey,David A. Mackey,Jamie E Craig,Stuart MacGregor,Tien Yin Wong,Tien Yin Wong +98 more
TL;DR: A meta-analysis on >20,000 individuals in European and Asian populations that identified 16 new loci associated with CCT at genome-wide significance showed that 2 CCT-associated loci conferred relatively large risks for keratoconus in 2 cohorts with 874 cases and 6,085 controls.
Journal ArticleDOI
Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma
Janey L. Wiggs,Brian L. Yaspan,Michael A. Hauser,Jae H. Kang,R. Rand Allingham,Lana M. Olson,Wael Abdrabou,Baojian Fan,Dan Y. Wang,Wendy Brodeur,Donald L. Budenz,Joseph Caprioli,Andrew Crenshaw,Kristy Crooks,E. DelBono,Kimberly F. Doheny,David S. Friedman,Douglas E. Gaasterland,Terry Gaasterland,Cathy C. Laurie,Richard K. Lee,Paul R. Lichter,Stephanie Loomis,Yutao Liu,Felipe A. Medeiros,Catherine A. McCarty,Daniel B. Mirel,Sayoko E. Moroi,David C. Musch,Anthony Realini,Frank W. Rozsa,Joel S. Schuman,Kathleen M. Scott,Kuldev Singh,Joshua D. Stein,Edward H. Trager,Paul C. VanVeldhuisen,Douglas Vollrath,Gadi Wollstein,Sachiko Yoneyama,Kang Zhang,Robert N. Weinreb,Jason Ernst,Manolis Kellis,Tomohiro Masuda,Donald J. Zack,Julia E. Richards,Margaret A. Pericak-Vance,Louis R. Pasquale,Jonathan L. Haines +49 more
TL;DR: The authors performed a meta-analysis of two independent genome-wide association studies for primary open angle glaucoma (POAG) followed by a normal pressure (NPG) defined by intraocular pressure (IOP) less than 22 mmHg subgroup analysis.