K
Ken Kurokawa
Researcher at Osaka University
Publications - 32
Citations - 3746
Ken Kurokawa is an academic researcher from Osaka University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 16, co-authored 32 publications receiving 3552 citations.
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Journal ArticleDOI
Complete Genome Sequence of Enterohemorrhagic Eschelichia coli O157:H7 and Genomic Comparison with a Laboratory Strain K-12
Tetsuya Hayashi,Kozo Makino,Makoto Ohnishi,Ken Kurokawa,Kazuo Ishii,Katsushi Yokoyama,Chang Gyun Han,Eiichi Ohtsubo,Keisuke Nakayama,Takahiro Murata,Masashi Tanaka,Toru Tobe,Tetsuya Iida,Hideto Takami,Takeshi Honda,Chihiro Sasakawa,Naotake Ogasawara,Teruo Yasunaga,Satoru Kuhara,Tadayoshi Shiba,Masahira Hattori,Hideo Shinagawa +21 more
TL;DR: The complete chromosome sequence of an O157:H7 strain isolated from the Sakai outbreak is reported, and the results of genomic comparison with a benign laboratory strain, K-12 MG1655, are identified, which may represent the fundamental backbone of the E. coli chromosome.
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Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V cholerae
Kozo Makino,Kenshiro Oshima,Kenshiro Oshima,Ken Kurokawa,Katsushi Yokoyama,Takayuki Uda,Kenichi Tagomori,Yoshio Iijima,Masatomo Najima,Masayuki Nakano,Atsushi Yamashita,Yoshino Kubota,Shigenobu Kimura,Teruo Yasunaga,Takeshi Honda,Hideo Shinagawa,Masahira Hattori,Tetsuya Iida +17 more
TL;DR: This finding explains clinical features of V parahaemolyticus infections, which commonly include inflammatory diarrhoea and in some cases systemic manifestations such as septicaemia, distinct from those of V cholerae infections,Which are generally associated with non-inflammatory diarrhoeA.
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Genome Sequence of an M3 Strain of Streptococcus pyogenes Reveals a Large-Scale Genomic Rearrangement in Invasive Strains and New Insights into Phage Evolution
Ichiro Nakagawa,Ken Kurokawa,Atsushi Yamashita,Masanobu Nakata,Yusuke Tomiyasu,Nobuo Okahashi,Shigetada Kawabata,Kiyoshi Yamazaki,Tadayoshi Shiba,Teruo Yasunaga,Hideo Hayashi,Masahira Hattori,Shigeyuki Hamada +12 more
TL;DR: Observations indicate that streptococcal phages represent important plasticity regions in the GAS chromosome where recombination between homologous phage genes can occur and result not only in new phage derivatives, but also in large chromosomal rearrangements.
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Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells.
Masatake Sato,Tohru Kimura,Ken Kurokawa,Yukiko Fujita,Koichiro Abe,Masaaki Masuhara,Teruo Yasunaga,Akihide Ryo,Mikio Yamamoto,Toru Nakano +9 more
TL;DR: Investigation of gene expression patterns of primordial germ cells (PGCs) and embryonic stem cells and a novel gene, PGC7, which was preferentially expressed in PGCs suggested that it might play an important role in the development of P GCs and oocytes.
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Diversification of Escherichia coli genomes: are bacteriophages the major contributors?
TL;DR: How the E. coli strains have diverged from a common ancestral strain, and how bacteriophages contributed to this process is discussed, and the possibility that such bacteria might function as 'phage factories', releasing a variety of chimeric or mosaic phages into the environment is raised.