Kendra Barker

TL;DR: High-accuracy, high-throughput, label-free classification of apoptosis, ferroptosis and necroptosis can be achieved with DHC, and models that used DHC-derived features to classify each form of cell death are developed and validated.

TL;DR: In this article, the authors compared the transcriptomes of melanocytes from healthy human skin, nevi, and melanomas arising from nevi and identified a set of microRNAs as highly expressed nevus-enriched transcripts.

TL;DR: McNeal et al. as discussed by the authors used genetic approaches to study melanocytes from moles and melanomas and found that increasing the levels of two of these microRNAs in melanocyte from human skin stopped the cells from growing and dividing by inhibiting a gene called AURKB.

TL;DR: A microRNA regulatory network is described that enforces BRAFV600E-induced growth arrest in human melanocytes during melanocytic nevus formation and provides a potential therapeutic intervention for melanoma prevention or treatment.