M
Marcus Urquijo
Researcher at Huntsman Cancer Institute
Publications - 2
Marcus Urquijo is an academic researcher from Huntsman Cancer Institute. The author has contributed to research in topics: Nevi and melanomas & Melanocytic nevus. The author has co-authored 2 publications.
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Posted ContentDOI
BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB
Andrew S. McNeal,Rachel L. Belote,Hanlin Zeng,Marcus Urquijo,Kendra Barker,Rodrigo Torres,Meghan Curtin,A. Hunter Shain,Robert H.I. Andtbacka,Robert H.I. Andtbacka,Sheri L. Holmen,Sheri L. Holmen,David H. Lum,Timothy H. McCalmont,Matthew W. VanBrocklin,Matthew W. VanBrocklin,Douglas Grossman,Douglas Grossman,Maria L. Wei,Maria L. Wei,Ursula E. Lang,Robert L. Judson-Torres,Robert L. Judson-Torres +22 more
TL;DR: In this article, the authors compared the transcriptomes of melanocytes from healthy human skin, nevi, and melanomas arising from nevi and identified a set of microRNAs as highly expressed nevus-enriched transcripts.
Journal ArticleDOI
BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB.
Andrew S. McNeal,Rachel L. Belote,Hanlin Zeng,Marcus Urquijo,Kendra Barker,Rodrigo Torres,Meghan Curtin,A. Hunter Shain,Robert H.I. Andtbacka,Robert H.I. Andtbacka,Sheri L. Holmen,Sheri L. Holmen,David H. Lum,Timothy H. McCalmont,Matthew W. VanBrocklin,Matthew W. VanBrocklin,Douglas Grossman,Douglas Grossman,Maria L. Wei,Ursula E. Lang,Robert L. Judson-Torres,Robert L. Judson-Torres +21 more
TL;DR: McNeal et al. as discussed by the authors used genetic approaches to study melanocytes from moles and melanomas and found that increasing the levels of two of these microRNAs in melanocyte from human skin stopped the cells from growing and dividing by inhibiting a gene called AURKB.