Kenji Yamamoto

TL;DR: The potential cytotoxicity of characterized QDs modified with various molecules suggested that the properties of QDs are not related to those of QD-core materials but to molecules covering the surface ofQDs.

TL;DR: The chemical process used to terminate the surfaces of the silicon quantum dots changes the internal electronic structure and thus plays an important role in the resultant emission wavelength and radiative lifetime, and ultimately determines the solubility.

TL;DR: Evaluated the cell damage caused by the quantum dots for biological applications and found that there is a range of concentration of MUA‐QDs where the cell viability decreased without cell death occurring and thus attention should be given when MUA-QDs are applied to living organisms even in low concentrations.

TL;DR: Photoluminescent semiconductor quantum dots were actively taken into the target cells by endocytotic pathways and remained stable luminescence against cell activation induced by concanavalin A, phytohemagglutinin, phorbol myristate acetate, and calcium ionophore A23187 and suggested that fluorescent probes of QDs might be useful as bioimaging tools for tracing target cells over the period of a week in vivo.

TL;DR: These techniques have the possibility that QDs can reveal the transduction of proteins and peptides into specific subcellular compartments as a powerful tool for studying intracellular analysis in vitro and even in vivo.