Kenneth K. Kwong

TL;DR: Cerebral blood flow was quantitatively mapped by monitoring the cerebral washout of H2 17O using rapid, single‐shot proton NMR imaging, and measured values for CBF ranged from 29 to 106 ml/min/100 g over a range of arterial pCO2.

TL;DR: Intrinsic changes in myocardial signal intensity were measured during dipyridamole induced coronary vasodilatation with T2*‐weighted echo planar MRI in healthy volunteers, consistent with the concept that changes inMyocardial deoxyhemoglobin content due to altered flow result in changes in magnetic susceptibility that can be detected on T2-weighted MR images.

TL;DR: In this paper, the locus coeruleus (LC) was identified as the initial site of hyperphosphorylated TAU aggregation, and as the number of LC neurons harboring TAU increases, TAU pathology emerges.

TL;DR: In severe dry eye, blink-inhibition strongly activated the visual cortex even after irritation due to corneal desiccation was removed by topical anesthesia and the blinking process, especially the rate, appears to be controlled in the orbitofrontal cortex.

TL;DR: The impact of regularization on the dynamic contrast‐to‐noise ratio (CNR) of regularized sensitivity encoding (SENSE) acquisitions is investigated by performing parametric simulations at various BOLD contrasts, acceleration rates, and sizes of the active brain areas and suggest that the detection power of SENSE fMRI can be improved by regularized reconstructions, compared to unregularized reconstruction.